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Ascorbate kills breast cancer cells by rewiring metabolism via redox imbalance and energy crisis.
Free Radic Biol Med. 2021 Feb 1;163:196-209. doi: 10.1016/j.freeradbiomed.2020.12.012. Epub 2020 Dec 23.
Free Radic Biol Med. 2021.
PMID: 33359260
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis.
Kiweler N, Delbrouck C, Pozdeev VI, Neises L, Soriano-Baguet L, Eiden K, Xian F, Benzarti M, Haase L, Koncina E, Schmoetten M, Jaeger C, Noman MZ, Vazquez A, Janji B, Dittmar G, Brenner D, Letellier E, Meiser J.
Kiweler N, et al. Among authors: neises l.
Nat Commun. 2022 May 16;13(1):2699. doi: 10.1038/s41467-022-30363-y.
Nat Commun. 2022.
PMID: 35577770
Free PMC article.
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A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well-Defined Protein-Protein Conjugates.
Baalmann M, Neises L, Bitsch S, Schneider H, Deweid L, Werther P, Ilkenhans N, Wolfring M, Ziegler MJ, Wilhelm J, Kolmar H, Wombacher R.
Baalmann M, et al. Among authors: neises l.
Angew Chem Int Ed Engl. 2020 Jul 27;59(31):12885-12893. doi: 10.1002/anie.201915079. Epub 2020 May 26.
Angew Chem Int Ed Engl. 2020.
PMID: 32342666
Free PMC article.
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Metabolic Potential of Cancer Cells in Context of the Metastatic Cascade.
Benzarti M, Delbrouck C, Neises L, Kiweler N, Meiser J.
Benzarti M, et al. Among authors: neises l.
Cells. 2020 Sep 5;9(9):2035. doi: 10.3390/cells9092035.
Cells. 2020.
PMID: 32899554
Free PMC article.
Review.
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Formate promotes invasion and metastasis in reliance on lipid metabolism.
Delbrouck C, Kiweler N, Chen O, Pozdeev VI, Haase L, Neises L, Oudin A, Fouquier d'Hérouël A, Shen R, Schlicker L, Halder R, Lesur A, Schuster A, Lorenz NI, Jaeger C, Feucherolles M, Frache G, Szpakowska M, Chevigne A, Ronellenfitsch MW, Moussay E, Piraud M, Skupin A, Schulze A, Niclou SP, Letellier E, Meiser J.
Delbrouck C, et al. Among authors: neises l.
Cell Rep. 2023 Sep 26;42(9):113034. doi: 10.1016/j.celrep.2023.113034. Epub 2023 Aug 30.
Cell Rep. 2023.
PMID: 37651228
Free article.
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Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut.
Becker B, Wottawa F, Bakr M, Koncina E, Mayr L, Kugler J, Yang G, Windross SJ, Neises L, Mishra N, Harris D, Tran F, Welz L, Schwärzler J, Bánki Z, Stengel ST, Ito G, Krötz C, Coleman OI, Jaeger C, Haller D, Paludan SR, Blumberg R, Kaser A, Cicin-Sain L, Schreiber S, Adolph TE, Letellier E, Rosenstiel P, Meiser J, Aden K.
Becker B, et al. Among authors: neises l.
iScience. 2024 Feb 8;27(3):109173. doi: 10.1016/j.isci.2024.109173. eCollection 2024 Mar 15.
iScience. 2024.
PMID: 38496294
Free PMC article.
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PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle.
Benzarti M, Neises L, Oudin A, Krötz C, Viry E, Gargiulo E, Pulido C, Schmoetten M, Pozdeev V, Lorenz NI, Ronellenfitsch MW, Sumpton D, Warmoes M, Jaeger C, Lesur A, Becker B, Moussay E, Paggetti J, Niclou SP, Letellier E, Meiser J.
Benzarti M, et al. Among authors: neises l.
Cell Rep. 2024 Mar 26;43(3):113868. doi: 10.1016/j.celrep.2024.113868. Epub 2024 Feb 28.
Cell Rep. 2024.
PMID: 38421868
Free article.
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GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
Watson DC, Bayik D, Storevik S, Moreino SS, Sprowls SA, Han J, Augustsson MT, Lauko A, Sravya P, Røsland GV, Troike K, Tronstad KJ, Wang S, Sarnow K, Kay K, Lunavat TR, Silver DJ, Dayal S, Joseph JV, Mulkearns-Hubert E, Ystaas LAR, Deshpande G, Guyon J, Zhou Y, Magaut CR, Seder J, Neises L, Williford SE, Meiser J, Scott AJ, Sajjakulnukit P, Mears JA, Bjerkvig R, Chakraborty A, Daubon T, Cheng F, Lyssiotis CA, Wahl DR, Hjelmeland AB, Hossain JA, Miletic H, Lathia JD.
Watson DC, et al. Among authors: neises l.
Nat Cancer. 2023 May;4(5):648-664. doi: 10.1038/s43018-023-00556-5. Epub 2023 May 11.
Nat Cancer. 2023.
PMID: 37169842
Free PMC article.
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