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Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse.
Muroňová J, Kherraf ZE, Giordani E, Lambert E, Eckert S, Cazin C, Amiri-Yekta A, Court M, Chevalier G, Martinez G, Neirijnck Y, Kühne F, Wehrli L, Klena N, Hamel V, De Macedo L, Escoffier J, Guichard P, Coutton C, Mustapha SFB, Kharouf M, Bouin AP, Zouari R, Thierry-Mieg N, Nef S, Geimer S, Loeuillet C, Ray PF, Arnoult C. Muroňová J, et al. Among authors: neirijnck y. Elife. 2024 Mar 5;12:RP86845. doi: 10.7554/eLife.86845. Elife. 2024. PMID: 38441556 Free PMC article.
The -KTS splice variant of WT1 is essential for ovarian determination in mice.
Gregoire EP, De Cian MC, Migale R, Perea-Gomez A, Schaub S, Bellido-Carreras N, Stévant I, Mayère C, Neirijnck Y, Loubat A, Rivaud P, Sopena ML, Lachambre S, Linssen MM, Hohenstein P, Lovell-Badge R, Nef S, Chalmel F, Schedl A, Chaboissier MC. Gregoire EP, et al. Among authors: neirijnck y. Science. 2023 Nov 3;382(6670):600-606. doi: 10.1126/science.add8831. Epub 2023 Nov 2. Science. 2023. PMID: 37917714 Free PMC article.
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.
Rossitto M, Déjardin S, Rands CM, Le Gras S, Migale R, Rafiee MR, Neirijnck Y, Pruvost A, Nguyen AL, Bossis G, Cammas F, Le Gallic L, Wilhelm D, Lovell-Badge R, Boizet-Bonhoure B, Nef S, Poulat F. Rossitto M, et al. Among authors: neirijnck y. Nat Commun. 2022 Jul 29;13(1):4412. doi: 10.1038/s41467-022-32061-1. Nat Commun. 2022. PMID: 35906245 Free PMC article.
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad.
Mayère C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, Bellido-Carreras N, Sararols P, Reeves R, Greenaway S, Simon M, Siggers P, Condrea D, Kühne F, Gantar I, Tang F, Stévant I, Batti L, Ghyselinck NB, Wilhelm D, Greenfield A, Capel B, Chaboissier MC, Nef S. Mayère C, et al. Among authors: neirijnck y. Sci Adv. 2022 May 27;8(21):eabm0972. doi: 10.1126/sciadv.abm0972. Epub 2022 May 25. Sci Adv. 2022. PMID: 35613264 Free PMC article.
Oligogenic heterozygous inheritance of sperm abnormalities in mouse.
Martinez G, Coutton C, Loeuillet C, Cazin C, Muroňová J, Boguenet M, Lambert E, Dhellemmes M, Chevalier G, Hograindleur JP, Vilpreux C, Neirijnck Y, Kherraf ZE, Escoffier J, Nef S, Ray PF, Arnoult C. Martinez G, et al. Among authors: neirijnck y. Elife. 2022 Apr 22;11:e75373. doi: 10.7554/eLife.75373. Elife. 2022. PMID: 35451961 Free PMC article.
Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B.
Cazin C, Neirijnck Y, Loeuillet C, Wehrli L, Kühne F, Lordey I, Mustapha SFB, Bouker A, Zouari R, Thierry-Mieg N, Nef S, Arnoult C, Ray PF, Kherraf ZE. Cazin C, et al. Among authors: neirijnck y. Cells. 2021 Dec 30;11(1):118. doi: 10.3390/cells11010118. Cells. 2021. PMID: 35011680 Free PMC article.
19 results