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Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2.
Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young K, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. Yin K, et al. Among authors: neidleman j. bioRxiv [Preprint]. 2023 Aug 4:2023.02.09.527892. doi: 10.1101/2023.02.09.527892. bioRxiv. 2023. PMID: 36798286 Free PMC article. Updated. Preprint.
Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection.
Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC. Roan NR, et al. Among authors: neidleman j. J Virol. 2014 Jul;88(13):7221-34. doi: 10.1128/JVI.00269-14. Epub 2014 Apr 16. J Virol. 2014. PMID: 24741080 Free PMC article.
Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.
Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. Neidleman JA, et al. PLoS Pathog. 2017 Feb 16;13(2):e1006163. doi: 10.1371/journal.ppat.1006163. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28207890 Free PMC article.
Semen amyloids participate in spermatozoa selection and clearance.
Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC. Roan NR, et al. Among authors: neidleman j. Elife. 2017 Jun 27;6:e24888. doi: 10.7554/eLife.24888. Elife. 2017. PMID: 28653619 Free PMC article.
Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.
George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. George AF, et al. Among authors: neidleman j. Hum Reprod. 2020 Mar 27;35(3):617-640. doi: 10.1093/humrep/deaa015. Hum Reprod. 2020. PMID: 32219408 Free PMC article.
Seminal Plasma-Derived Extracellular-Vesicle Fractions from HIV-Infected Men Exhibit Unique MicroRNA Signatures and Induce a Proinflammatory Response in Cells Isolated from the Female Reproductive Tract.
Marques de Menezes EG, Jang K, George AF, Nyegaard M, Neidleman J, Inglis HC, Danesh A, Deng X, Afshari A, Kim YH, Billaud JN, Marson K, Pilcher CD, Pillai SK, Norris PJ, Roan NR. Marques de Menezes EG, et al. Among authors: neidleman j. J Virol. 2020 Jul 30;94(16):e00525-20. doi: 10.1128/JVI.00525-20. Print 2020 Jul 30. J Virol. 2020. PMID: 32434889 Free PMC article.
40 results