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Xanthene and xanthone derivatives as G-quadruplex stabilizing ligands.
Altieri A, Alvino A, Ohnmacht S, Ortaggi G, Neidle S, Nocioni D, Franceschin M, Bianco A. Altieri A, et al. Among authors: neidle s. Molecules. 2013 Oct 30;18(11):13446-70. doi: 10.3390/molecules181113446. Molecules. 2013. PMID: 24177701 Free PMC article.
Natural and synthetic G-quadruplex interactive berberine derivatives.
Franceschin M, Rossetti L, D'Ambrosio A, Schirripa S, Bianco A, Ortaggi G, Savino M, Schultes C, Neidle S. Franceschin M, et al. Among authors: neidle s. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1707-11. doi: 10.1016/j.bmcl.2005.12.001. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377184
N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage.
Casagrande V, Salvati E, Alvino A, Bianco A, Ciammaichella A, D'Angelo C, Ginnari-Satriani L, Serrilli AM, Iachettini S, Leonetti C, Neidle S, Ortaggi G, Porru M, Rizzo A, Franceschin M, Biroccio A. Casagrande V, et al. Among authors: neidle s. J Med Chem. 2011 Mar 10;54(5):1140-56. doi: 10.1021/jm1013665. Epub 2011 Jan 31. J Med Chem. 2011. PMID: 21280624
Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer.
Mitchell T, Ramos-Montoya A, Di Antonio M, Murat P, Ohnmacht S, Micco M, Jurmeister S, Fryer L, Balasubramanian S, Neidle S, Neal DE. Mitchell T, et al. Among authors: neidle s. Biochemistry. 2013 Feb 26;52(8):1429-36. doi: 10.1021/bi301349c. Epub 2013 Feb 11. Biochemistry. 2013. PMID: 23363071
383 results