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Implication of type 4 NADPH oxidase (NOX4) in tauopathy.
Luengo E, Trigo-Alonso P, Fernández-Mendívil C, Nuñez Á, Campo MD, Porrero C, García-Magro N, Negredo P, Senar S, Sánchez-Ramos C, Bernal JA, Rábano A, Hoozemans J, Casas AI, Schmidt HHHW, López MG. Luengo E, et al. Among authors: negredo p. Redox Biol. 2022 Feb;49:102210. doi: 10.1016/j.redox.2021.102210. Epub 2021 Dec 10. Redox Biol. 2022. PMID: 34922273 Free PMC article.
The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2.
Parada E, Egea J, Buendia I, Negredo P, Cunha AC, Cardoso S, Soares MP, López MG. Parada E, et al. Among authors: negredo p. Antioxid Redox Signal. 2013 Oct 10;19(11):1135-48. doi: 10.1089/ars.2012.4671. Epub 2013 Feb 25. Antioxid Redox Signal. 2013. PMID: 23311871 Free PMC article.
Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux.
Luengo E, Buendia I, Fernández-Mendívil C, Trigo-Alonso P, Negredo P, Michalska P, Hernández-García B, Sánchez-Ramos C, Bernal JA, Ikezu T, León R, López MG. Luengo E, et al. Among authors: negredo p. J Pineal Res. 2019 Aug;67(1):e12578. doi: 10.1111/jpi.12578. Epub 2019 Apr 29. J Pineal Res. 2019. PMID: 30943316
30 results