Highly(≥98%) Selective Trisubstituted Alkene Synthesis of Wide Applicability via Fluoride-Promoted Pd-Catalyzed Cross-Coupling of Alkenylboranes.
Negishi EI, Tobrman T, Rao H, Xu S, Lee CT.
Negishi EI, et al.
Isr J Chem. 2010 Dec 1;50(5-6):696-701. doi: 10.1002/ijch.201000051.
Isr J Chem. 2010.
PMID: 23966749
Free PMC article.
(Z)-beta-bromo-1-propenyl(pinacol)borane(4), recently made available in 85% yield as a 98% isomerically pure compound via bromoboration of 1-propyne, has been converted to beta-alkyl-, aryl-, and alkenyl-substituted (Z)-2-methyl-1-alkenyl(pinacol)boranes(2a) in ca. 75% yield base …
(Z)-beta-bromo-1-propenyl(pinacol)borane(4), recently made available in 85% yield as a 98% isomerically pure compound via bromoboration of 1 …