Negi A - Search Results

1

Development of Mcl-1 inhibitors for cancer therapy.

Negi A, Murphy PV. Negi A, et al. Eur J Med Chem. 2021 Jan 15;210:113038. doi: 10.1016/j.ejmech.2020.113038. Epub 2020 Nov 24. Eur J Med Chem. 2021. PMID: 33333396 Free article. Review.

2

Synthesis of 2-alkoxy and 2-benzyloxy analogues of estradiol as anti-breast cancer agents through microtubule stabilization.

Sathish Kumar B, Kumar A, Singh J, Hasanain M, Singh A, Fatima K, Yadav DK, Shukla V, Luqman S, Khan F, Chanda D, Sarkar J, Konwar R, Dwivedi A, Negi AS. Sathish Kumar B, et al. Among authors: negi as. Eur J Med Chem. 2014 Oct 30;86:740-51. doi: 10.1016/j.ejmech.2014.09.033. Epub 2014 Sep 10. Eur J Med Chem. 2014. PMID: 25238172

3

Decorated macrocycles via ring-closing double-reductive amination. identification of an apoptosis inducer of leukemic cells that at least partially antagonizes a 5-HT2 receptor.

Zhou J, Reidy M, O'Reilly C, Jarikote DV, Negi A, Samali A, Szegezdi E, Murphy PV. Zhou J, et al. Among authors: negi a. Org Lett. 2015 Apr 3;17(7):1672-5. doi: 10.1021/acs.orglett.5b00404. Epub 2015 Mar 16. Org Lett. 2015. PMID: 25774456

4

Antiproliferative efficacy of curcumin mimics through microtubule destabilization.

Khwaja S, Fatima K, Hasanain M, Behera C, Kour A, Singh A, Luqman S, Sarkar J, Chanda D, Shanker K, Gupta AK, Mondhe DM, Negi AS. Khwaja S, et al. Among authors: negi as. Eur J Med Chem. 2018 May 10;151:51-61. doi: 10.1016/j.ejmech.2018.03.063. Epub 2018 Mar 26. Eur J Med Chem. 2018. PMID: 29605808

5

Ligand design for somatostatin receptor isoforms 4 and 5.

Negi A, Zhou J, Sweeney S, Murphy PV. Negi A, et al. Eur J Med Chem. 2019 Feb 1;163:148-159. doi: 10.1016/j.ejmech.2018.11.030. Epub 2018 Nov 17. Eur J Med Chem. 2019. PMID: 30503939

6

N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines.

Zhou J, Negi A, Mirallai SI, Warta R, Herold-Mende C, Carty MP, Ye XS, Murphy PV. Zhou J, et al. Among authors: negi a. Bioorg Chem. 2019 Mar;84:418-433. doi: 10.1016/j.bioorg.2018.12.003. Epub 2018 Dec 4. Bioorg Chem. 2019. PMID: 30554081

7

Multi-targeting protein-protein interaction inhibitors: Evolution of macrocyclic ligands with embedded carbohydrates (MECs) to improve selectivity.

Negi A, Reilly CO, Jarikote DV, Zhou J, Murphy PV. Negi A, et al. Eur J Med Chem. 2019 Aug 15;176:292-309. doi: 10.1016/j.ejmech.2019.04.064. Epub 2019 May 11. Eur J Med Chem. 2019. PMID: 31112891

8

Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization.

Prakasham AP, Saxena AK, Luqman S, Chanda D, Kaur T, Gupta A, Yadav DK, Chanotiya CS, Shanker K, Khan F, Negi AS. Prakasham AP, et al. Among authors: negi as. Bioorg Med Chem. 2012 May 1;20(9):3049-57. doi: 10.1016/j.bmc.2012.02.057. Epub 2012 Mar 14. Bioorg Med Chem. 2012. PMID: 22472045

9

Recent advancements in small molecule inhibitors of insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase as anticancer agents.

Negi A, Ramarao P, Kumar R. Negi A, et al. Mini Rev Med Chem. 2013 Apr 1;13(5):653-81. doi: 10.2174/1389557511313050004. Mini Rev Med Chem. 2013. PMID: 23373648 Review.

10

Synthesis of neolignans as microtubule stabilisers.

Sathish Kumar B, Singh A, Kumar A, Singh J, Hasanain M, Singh A, Masood N, Yadav DK, Konwar R, Mitra K, Sarkar J, Luqman S, Pal A, Khan F, Chanda D, Negi AS. Sathish Kumar B, et al. Among authors: negi as. Bioorg Med Chem. 2014 Feb 15;22(4):1342-54. doi: 10.1016/j.bmc.2013.12.067. Epub 2014 Jan 9. Bioorg Med Chem. 2014. PMID: 24457094

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