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Page 1
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.
Zhao JH, Stacey D, Eriksson N, Macdonald-Dunlop E, Hedman ÅK, Kalnapenkis A, Enroth S, Cozzetto D, Digby-Bell J, Marten J, Folkersen L, Herder C, Jonsson L, Bergen SE, Gieger C, Needham EJ, Surendran P; Estonian Biobank Research Team; Paul DS, Polasek O, Thorand B, Grallert H, Roden M, Võsa U, Esko T, Hayward C, Johansson Å, Gyllensten U, Powell N, Hansson O, Mattsson-Carlgren N, Joshi PK, Danesh J, Padyukov L, Klareskog L, Landén M, Wilson JF, Siegbahn A, Wallentin L, Mälarstig A, Butterworth AS, Peters JE. Zhao JH, et al. Among authors: needham ej. Nat Immunol. 2023 Sep;24(9):1540-1551. doi: 10.1038/s41590-023-01588-w. Epub 2023 Aug 10. Nat Immunol. 2023. PMID: 37563310 Free PMC article.
Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.
Zhao JH, Stacey D, Eriksson N, Macdonald-Dunlop E, Hedman ÅK, Kalnapenkis A, Enroth S, Cozzetto D, Digby-Bell J, Marten J, Folkersen L, Herder C, Jonsson L, Bergen SE, Gieger C, Needham EJ, Surendran P; Estonian Biobank Research Team; Paul DS, Polasek O, Thorand B, Grallert H, Roden M, Võsa U, Esko T, Hayward C, Johansson Å, Gyllensten U, Powell N, Hansson O, Mattsson-Carlgren N, Joshi PK, Danesh J, Padyukov L, Klareskog L, Landén M, Wilson JF, Siegbahn A, Wallentin L, Mälarstig A, Butterworth AS, Peters JE. Zhao JH, et al. Among authors: needham ej. Nat Immunol. 2023 Nov;24(11):1960. doi: 10.1038/s41590-023-01635-6. Nat Immunol. 2023. PMID: 37679551 Free PMC article. No abstract available.
Targets mapped for almost all human kinase enzymes.
Humphrey SJ, Needham EJ. Humphrey SJ, et al. Among authors: needham ej. Nature. 2023 Jan;613(7945):637-638. doi: 10.1038/d41586-022-04583-7. Nature. 2023. PMID: 36631581 No abstract available.
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Wood GK, Collie C, Digby R, Ren A, Norton E, Leibowitz M, Ebrahimi S, Fower A, Fox H, Tato E, Ellul MA, Sunderland G, Held M, Hetherington C, Egbe FN, Palmos A, Stirrups K, Grundmann A, Chiollaz AC, Sanchez JC, Stewart JP, Griffiths M, Solomon T, Breen G, Coles AJ, Kingston N, Bradley JR, Chinnery PF, Cavanagh J, Irani SR, Vincent A, Baillie JK, Openshaw PJ, Semple MG; ISARIC4C Investigators; COVID-CNS Consortium; Taams LS, Menon DK. Michael BD, et al. Among authors: needham ej. Nat Commun. 2024 Apr 4;15(1):2918. doi: 10.1038/s41467-024-47320-6. Nat Commun. 2024. PMID: 38575615 Free PMC article. No abstract available.
Erratum: Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet.
Yau B, Naghiloo S, Diaz-Vegas A, Carr AV, Van Gerwen J, Needham EJ, Jevon D, Chen SY, Hoehn KL, Brandon AE, Macia L, Cooney GJ, Shortreed MR, Smith LM, Keller MP, Thorn P, Larance M, James DE, Humphrey SJ, Kebede MA. Yau B, et al. Among authors: needham ej. iScience. 2023 Dec 14;27(1):108707. doi: 10.1016/j.isci.2023.108707. eCollection 2024 Jan 19. iScience. 2023. PMID: 38188515 Free PMC article.
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Wood GK, Collie C, Digby R, Ren A, Norton E, Leibowitz M, Ebrahimi S, Fower A, Fox H, Tato E, Ellul MA, Sunderland G, Held M, Hetherington C, Egbe FN, Palmos A, Stirrups K, Grundmann A, Chiollaz AC, Sanchez JC, Stewart JP, Griffiths M, Solomon T, Breen G, Coles AJ, Kingston N, Bradley JR, Chinnery PF, Cavanagh J, Irani SR, Vincent A, Baillie JK, Openshaw PJ, Semple MG; ISARIC4C Investigators; COVID-CNS Consortium; Taams LS, Menon DK. Michael BD, et al. Among authors: needham ej. Nat Commun. 2023 Dec 22;14(1):8487. doi: 10.1038/s41467-023-42320-4. Nat Commun. 2023. PMID: 38135686 Free PMC article.
Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment.
Rudraraju R, Gartner MJ, Neil JA, Stout ES, Chen J, Needham EJ, See M, Mackenzie-Kludas C, Yang Lee LY, Wang M, Pointer H, Karavendzas K, Abu-Bonsrah D, Drew D, Yang Sun YB, Tan JP, Sun G, Salavaty A, Charitakis N, Nim HT, Currie PD, Tham WH, Porrello E, Polo JM, Humphrey SJ, Ramialison M, Elliott DA, Subbarao K. Rudraraju R, et al. Among authors: needham ej. Stem Cell Reports. 2023 Jun 13;18(6):1308-1324. doi: 10.1016/j.stemcr.2023.05.007. Stem Cell Reports. 2023. PMID: 37315523 Free PMC article.
Vascular cells improve functionality of human cardiac organoids.
Voges HK, Foster SR, Reynolds L, Parker BL, Devilée L, Quaife-Ryan GA, Fortuna PRJ, Mathieson E, Fitzsimmons R, Lor M, Batho C, Reid J, Pocock M, Friedman CE, Mizikovsky D, Francois M, Palpant NJ, Needham EJ, Peralta M, Monte-Nieto GD, Jones LK, Smyth IM, Mehdiabadi NR, Bolk F, Janbandhu V, Yao E, Harvey RP, Chong JJH, Elliott DA, Stanley EG, Wiszniak S, Schwarz Q, James DE, Mills RJ, Porrello ER, Hudson JE. Voges HK, et al. Among authors: needham ej. Cell Rep. 2023 May 30;42(5):112322. doi: 10.1016/j.celrep.2023.112322. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37105170 Free article.
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance.
Fazakerley DJ, van Gerwen J, Cooke KC, Duan X, Needham EJ, Díaz-Vegas A, Madsen S, Norris DM, Shun-Shion AS, Krycer JR, Burchfield JG, Yang P, Wade MR, Brozinick JT, James DE, Humphrey SJ. Fazakerley DJ, et al. Among authors: needham ej. Nat Commun. 2023 Feb 18;14(1):923. doi: 10.1038/s41467-023-36549-2. Nat Commun. 2023. PMID: 36808134 Free PMC article.
33 results