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Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections.
Nuccitelli A, Cozzi R, Gourlay LJ, Donnarumma D, Necchi F, Norais N, Telford JL, Rappuoli R, Bolognesi M, Maione D, Grandi G, Rinaudo CD. Nuccitelli A, et al. Among authors: necchi f. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10278-83. doi: 10.1073/pnas.1106590108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593422 Free PMC article.
Sortase A substrate specificity in GBS pilus 2a cell wall anchoring.
Necchi F, Nardi-Dei V, Biagini M, Assfalg M, Nuccitelli A, Cozzi R, Norais N, Telford JL, Rinaudo CD, Grandi G, Maione D. Necchi F, et al. PLoS One. 2011;6(10):e25300. doi: 10.1371/journal.pone.0025300. Epub 2011 Oct 4. PLoS One. 2011. PMID: 21991306 Free PMC article.
Investigating the Role of Antigen Orientation on the Immune Response Elicited by Neisseria meningitidis Factor H Binding Protein on GMMA.
Alfini R, Brunelli B, Bartolini E, Carducci M, Luzzi E, Ferlicca F, Buccato S, Galli B, Lo Surdo P, Scarselli M, Romagnoli G, Cartocci E, Maione D, Savino S, Necchi F, Delany I, Micoli F. Alfini R, et al. Among authors: necchi f. Vaccines (Basel). 2022 Jul 26;10(8):1182. doi: 10.3390/vaccines10081182. Vaccines (Basel). 2022. PMID: 35893831 Free PMC article.
Rational Design of a Glycoconjugate Vaccine against Group A Streptococcus.
Di Benedetto R, Mancini F, Carducci M, Gasperini G, Moriel DG, Saul A, Necchi F, Rappuoli R, Micoli F. Di Benedetto R, et al. Among authors: necchi f. Int J Mol Sci. 2020 Nov 13;21(22):8558. doi: 10.3390/ijms21228558. Int J Mol Sci. 2020. PMID: 33202815 Free PMC article.
Generalized Modules for Membrane Antigens as Carrier for Polysaccharides: Impact of Sugar Length, Density, and Attachment Site on the Immune Response Elicited in Animal Models.
Micoli F, Alfini R, Di Benedetto R, Necchi F, Schiavo F, Mancini F, Carducci M, Oldrini D, Pitirollo O, Gasperini G, Balocchi C, Bechi N, Brunelli B, Piccioli D, Adamo R. Micoli F, et al. Among authors: necchi f. Front Immunol. 2021 Sep 14;12:719315. doi: 10.3389/fimmu.2021.719315. eCollection 2021. Front Immunol. 2021. PMID: 34594333 Free PMC article.
50 results