Nebert DW - Search Results

1

Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line.

Dragin N, Uno S, Wang B, Dalton TP, Nebert DW. Dragin N, et al. Among authors: nebert dw. Biochem Biophys Res Commun. 2007 Aug 3;359(3):635-42. doi: 10.1016/j.bbrc.2007.05.202. Epub 2007 Jun 6. Biochem Biophys Res Commun. 2007. PMID: 17560947 Free PMC article.

2

Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.

Uno S, Wang B, Shertzer HG, Nebert DW, Dalton TP. Uno S, et al. Among authors: nebert dw. Biochem Biophys Res Commun. 2003 Dec 12;312(2):494-9. doi: 10.1016/j.bbrc.2003.10.145. Biochem Biophys Res Commun. 2003. PMID: 14637164

3

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.

Uno S, Dalton TP, Sinclair PR, Gorman N, Wang B, Smith AG, Miller ML, Shertzer HG, Nebert DW. Uno S, et al. Among authors: nebert dw. Toxicol Appl Pharmacol. 2004 May 1;196(3):410-21. doi: 10.1016/j.taap.2004.01.014. Toxicol Appl Pharmacol. 2004. PMID: 15094312

4

Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.

Jiang Z, Dalton TP, Jin L, Wang B, Tsuneoka Y, Shertzer HG, Deka R, Nebert DW. Jiang Z, et al. Among authors: nebert dw. Hum Mutat. 2005 Feb;25(2):196-206. doi: 10.1002/humu.20134. Hum Mutat. 2005. PMID: 15643613

5

Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.

Derkenne S, Curran CP, Shertzer HG, Dalton TP, Dragin N, Nebert DW. Derkenne S, et al. Among authors: nebert dw. Pharmacogenet Genomics. 2005 Jul;15(7):503-11. doi: 10.1097/01.fpc.0000167326.00411.50. Pharmacogenet Genomics. 2005. PMID: 15970798

6

Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.

Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, Shertzer HG, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: nebert dw. Mol Pharmacol. 2006 Apr;69(4):1103-14. doi: 10.1124/mol.105.021501. Epub 2005 Dec 23. Mol Pharmacol. 2006. PMID: 16377763

7

Comparison of mouse hepatic mitochondrial versus microsomal cytochromes P450 following TCDD treatment.

Genter MB, Clay CD, Dalton TP, Dong H, Nebert DW, Shertzer HG. Genter MB, et al. Among authors: nebert dw. Biochem Biophys Res Commun. 2006 Apr 21;342(4):1375-81. doi: 10.1016/j.bbrc.2006.02.121. Epub 2006 Feb 28. Biochem Biophys Res Commun. 2006. PMID: 16516144

8

For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.

Dragin N, Dalton TP, Miller ML, Shertzer HG, Nebert DW. Dragin N, et al. Among authors: nebert dw. J Biol Chem. 2006 Jul 7;281(27):18591-600. doi: 10.1074/jbc.M601159200. Epub 2006 Apr 24. J Biol Chem. 2006. PMID: 16636061 Free article.

9

Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs.

Genter MB, Marlowe J, Kevin Kerzee J, Dragin N, Puga A, Dalton TP, Nebert DW. Genter MB, et al. Among authors: nebert dw. Biochem Biophys Res Commun. 2006 Sep 15;348(1):120-3. doi: 10.1016/j.bbrc.2006.07.025. Epub 2006 Jul 14. Biochem Biophys Res Commun. 2006. PMID: 16876762

10

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.

Uno S, Dragin N, Miller ML, Dalton TP, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: nebert dw. Free Radic Biol Med. 2008 Feb 15;44(4):570-83. doi: 10.1016/j.freeradbiomed.2007.10.044. Epub 2007 Nov 12. Free Radic Biol Med. 2008. PMID: 17997381 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

524 results

Search Page