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Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding.
Sekhon UDS, Swingle K, Girish A, Luc N, de la Fuente M, Alvikas J, Haldeman S, Hassoune A, Shah K, Kim Y, Eppell S, Capadona J, Shoffstall A, Neal MD, Li W, Nieman M, Sen Gupta A. Sekhon UDS, et al. Among authors: neal md. Sci Transl Med. 2022 Jan 26;14(629):eabb8975. doi: 10.1126/scitranslmed.abb8975. Epub 2022 Jan 26. Sci Transl Med. 2022. PMID: 35080915 Free PMC article.
Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage.
Hickman DA, Pawlowski CL, Shevitz A, Luc NF, Kim A, Girish A, Marks J, Ganjoo S, Huang S, Niedoba E, Sekhon UDS, Sun M, Dyer M, Neal MD, Kashyap VS, Sen Gupta A. Hickman DA, et al. Among authors: neal md. Sci Rep. 2018 Feb 15;8(1):3118. doi: 10.1038/s41598-018-21384-z. Sci Rep. 2018. PMID: 29449604 Free PMC article.
Platelet-derived extracellular vesicles released after trauma promote hemostasis and contribute to DVT in mice.
Dyer MR, Alexander W, Hassoune A, Chen Q, Brzoska T, Alvikas J, Liu Y, Haldeman S, Plautz W, Loughran P, Li H, Boone B, Sadovsky Y, Sundd P, Zuckerbraun BS, Neal MD. Dyer MR, et al. Among authors: neal md. J Thromb Haemost. 2019 Oct;17(10):1733-1745. doi: 10.1111/jth.14563. Epub 2019 Jul 28. J Thromb Haemost. 2019. PMID: 31294514 Free PMC article.
Pass interference: Getting in the way of platelets.
Lee RH, Neal MD, Sen Gupta A. Lee RH, et al. Among authors: neal md. J Thromb Haemost. 2019 Sep;17(9):1414-1416. doi: 10.1111/jth.14536. Epub 2019 Jul 12. J Thromb Haemost. 2019. PMID: 31301115 Free article. No abstract available.
234 results