Nayak D - Search Results

1

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity.

Lv D, Pal P, Liu X, Jia Y, Thummuri D, Zhang P, Hu W, Pei J, Zhang Q, Zhou S, Khan S, Zhang X, Hua N, Yang Q, Arango S, Zhang W, Nayak D, Olsen SK, Weintraub ST, Hromas R, Konopleva M, Yuan Y, Zheng G, Zhou D. Lv D, et al. Among authors: nayak d. Nat Commun. 2021 Nov 25;12(1):6896. doi: 10.1038/s41467-021-27210-x. Nat Commun. 2021. PMID: 34824248 Free PMC article.

2

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.

Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK. Rut W, et al. Among authors: nayak d. Sci Adv. 2020 Oct 16;6(42):eabd4596. doi: 10.1126/sciadv.abd4596. Print 2020 Oct. Sci Adv. 2020. PMID: 33067239 Free PMC article.

3

Clearing the air: Uniquely engaging furin as an approach to cystic fibrosis therapy.

Nayak D, Wasmuth EV, Olsen SK. Nayak D, et al. Cell Chem Biol. 2022 Jun 16;29(6):927-929. doi: 10.1016/j.chembiol.2022.05.011. Cell Chem Biol. 2022. PMID: 35714591 Free PMC article.

4

Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6.

Yuan L, Gao F, Lv Z, Nayak D, Nayak A, Santos Bury PD, Cano KE, Jia L, Oleinik N, Atilgan FC, Ogretmen B, Williams KM, Davies C, El Oualid F, Wasmuth EV, Olsen SK. Yuan L, et al. Among authors: nayak a, nayak d. Nat Commun. 2022 Aug 19;13(1):4880. doi: 10.1038/s41467-022-32613-5. Nat Commun. 2022. PMID: 35986001 Free PMC article.

5

Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease.

Nayak D, Dos Santos Bury P, Drag M, Nijkerk AN, El Oualid F, Olsen SK. Nayak D, et al. Methods Mol Biol. 2023;2591:171-188. doi: 10.1007/978-1-0716-2803-4_11. Methods Mol Biol. 2023. PMID: 36350549

6

Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer.

Afsar M, Liu G, Jia L, Ruben EA, Nayak D, Sayyad Z, Bury PDS, Cano KE, Nayak A, Zhao XR, Shukla A, Sung P, Wasmuth EV, Gack MU, Olsen SK. Afsar M, et al. Among authors: nayak a, nayak d. Nat Commun. 2023 Aug 8;14(1):4786. doi: 10.1038/s41467-023-39780-z. Nat Commun. 2023. PMID: 37553340 Free PMC article.

7

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.

Nayak D, Lv D, Yuan Y, Zhang P, Hu W, Nayak A, Ruben EA, Lv Z, Sung P, Hromas R, Zheng G, Zhou D, Olsen SK. Nayak D, et al. Nat Commun. 2024 Mar 29;15(1):2743. doi: 10.1038/s41467-024-46922-4. Nat Commun. 2024. PMID: 38548768 Free PMC article.

8

Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design.

Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK. Rut W, et al. Among authors: nayak d. bioRxiv [Preprint]. 2020 Apr 29:2020.04.29.068890. doi: 10.1101/2020.04.29.068890. bioRxiv. 2020. PMID: 32511411 Free PMC article. Updated. Preprint.

9

Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts.

Strub DJ, Talma M, Strub M, Rut W, Zmudzinski M, Brud W, Neyts J, Vangeel L, Zhang L, Sun X, Lv Z, Nayak D, Olsen SK, Hilgenfeld R, Jochmans D, Drąg M. Strub DJ, et al. Among authors: nayak d. Sci Rep. 2022 Aug 20;12(1):14230. doi: 10.1038/s41598-022-18676-w. Sci Rep. 2022. PMID: 35987981 Free PMC article.

10

Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PL^pro and M^pro proteases, and nsp14 guanine N7-methyltransferase.

Zmudzinski M, Rut W, Olech K, Granda J, Giurg M, Burda-Grabowska M, Kaleta R, Zgarbova M, Kasprzyk R, Zhang L, Sun X, Lv Z, Nayak D, Kesik-Brodacka M, Olsen SK, Weber J, Hilgenfeld R, Jemielity J, Drag M. Zmudzinski M, et al. Among authors: nayak d. Sci Rep. 2023 Jun 6;13(1):9161. doi: 10.1038/s41598-023-35907-w. Sci Rep. 2023. PMID: 37280236 Free PMC article.

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