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Reproducing human and cross-species drug toxicities using a Liver-Chip.
Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA. Jang KJ, et al. Among authors: nawroth j. Sci Transl Med. 2019 Nov 6;11(517):eaax5516. doi: 10.1126/scitranslmed.aax5516. Sci Transl Med. 2019. PMID: 31694927
Modeling alcohol-associated liver disease in a human Liver-Chip.
Nawroth JC, Petropolis DB, Manatakis DV, Maulana TI, Burchett G, Schlünder K, Witt A, Shukla A, Kodella K, Ronxhi J, Kulkarni G, Hamilton G, Seki E, Lu S, Karalis KC. Nawroth JC, et al. Cell Rep. 2021 Jul 20;36(3):109393. doi: 10.1016/j.celrep.2021.109393. Cell Rep. 2021. PMID: 34289365 Free PMC article.
Stem cell-based Lung-on-Chips: The best of both worlds?
Nawroth JC, Barrile R, Conegliano D, van Riet S, Hiemstra PS, Villenave R. Nawroth JC, et al. Adv Drug Deliv Rev. 2019 Feb 1;140:12-32. doi: 10.1016/j.addr.2018.07.005. Epub 2018 Jul 25. Adv Drug Deliv Rev. 2019. PMID: 30009883 Free PMC article. Review.
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells.
Maoz BM, Herland A, FitzGerald EA, Grevesse T, Vidoudez C, Pacheco AR, Sheehy SP, Park TE, Dauth S, Mannix R, Budnik N, Shores K, Cho A, Nawroth JC, Segrè D, Budnik B, Ingber DE, Parker KK. Maoz BM, et al. Nat Biotechnol. 2018 Oct;36(9):865-874. doi: 10.1038/nbt.4226. Epub 2018 Aug 20. Nat Biotechnol. 2018. PMID: 30125269 Free PMC article.
Robotic fluidic coupling and interrogation of multiple vascularized organ chips.
Novak R, Ingram M, Marquez S, Das D, Delahanty A, Herland A, Maoz BM, Jeanty SSF, Somayaji MR, Burt M, Calamari E, Chalkiadaki A, Cho A, Choe Y, Chou DB, Cronce M, Dauth S, Divic T, Fernandez-Alcon J, Ferrante T, Ferrier J, FitzGerald EA, Fleming R, Jalili-Firoozinezhad S, Grevesse T, Goss JA, Hamkins-Indik T, Henry O, Hinojosa C, Huffstater T, Jang KJ, Kujala V, Leng L, Mannix R, Milton Y, Nawroth J, Nestor BA, Ng CF, O'Connor B, Park TE, Sanchez H, Sliz J, Sontheimer-Phelps A, Swenor B, Thompson G 2nd, Touloumes GJ, Tranchemontagne Z, Wen N, Yadid M, Bahinski A, Hamilton GA, Levner D, Levy O, Przekwas A, Prantil-Baun R, Parker KK, Ingber DE. Novak R, et al. Among authors: nawroth j. Nat Biomed Eng. 2020 Apr;4(4):407-420. doi: 10.1038/s41551-019-0497-x. Epub 2020 Jan 27. Nat Biomed Eng. 2020. PMID: 31988458 Free PMC article.
Organ-on-a-Chip Systems for Women's Health Applications.
Nawroth J, Rogal J, Weiss M, Brucker SY, Loskill P. Nawroth J, et al. Adv Healthc Mater. 2018 Jan;7(2). doi: 10.1002/adhm.201700550. Epub 2017 Oct 6. Adv Healthc Mater. 2018. PMID: 28985032 Review.
29 results