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Design, Synthesis, and In Silico Multitarget Pharmacological Simulations of Acid Bioisosteres with a Validated In Vivo Antihyperglycemic Effect.
Domínguez-Mendoza EA, Galván-Ciprés Y, Martínez-Miranda J, Miranda-González C, Colín-Lozano B, Hernández-Núñez E, Hernández-Bolio GI, Palomino-Hernández O, Navarrete-Vazquez G. Domínguez-Mendoza EA, et al. Molecules. 2021 Feb 4;26(4):799. doi: 10.3390/molecules26040799. Molecules. 2021. PMID: 33557136 Free PMC article.
Design, synthesis and in vitro antiprotozoal activity of benzimidazole-pentamidine hybrids.
Torres-Gómez H, Hernández-Núñez E, León-Rivera I, Guerrero-Alvarez J, Cedillo-Rivera R, Moo-Puc R, Argotte-Ramos R, Rodríguez-Gutiérrez Mdel C, Chan-Bacab MJ, Navarrete-Vázquez G. Torres-Gómez H, et al. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3147-51. doi: 10.1016/j.bmcl.2008.05.009. Epub 2008 May 4. Bioorg Med Chem Lett. 2008. PMID: 18486471
Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity.
Navarrete-Vazquez G, Paoli P, León-Rivera I, Villalobos-Molina R, Medina-Franco JL, Ortiz-Andrade R, Estrada-Soto S, Camici G, Diaz-Coutiño D, Gallardo-Ortiz I, Martinez-Mayorga K, Moreno-Díaz H. Navarrete-Vazquez G, et al. Bioorg Med Chem. 2009 May 1;17(9):3332-41. doi: 10.1016/j.bmc.2009.03.042. Epub 2009 Mar 26. Bioorg Med Chem. 2009. PMID: 19362487
Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors.
Navarrete-Vazquez G, Ramírez-Martínez M, Estrada-Soto S, Nava-Zuazo C, Paoli P, Camici G, Escalante-García J, Medina-Franco JL, López-Vallejo F, Ortiz-Andrade R. Navarrete-Vazquez G, et al. Eur J Med Chem. 2012 Jul;53:346-55. doi: 10.1016/j.ejmech.2012.04.025. Epub 2012 Apr 26. Eur J Med Chem. 2012. PMID: 22583779
Discovery of thiazolidine-2,4-dione/biphenylcarbonitrile hybrid as dual PPAR α/γ modulator with antidiabetic effect: in vitro, in silico and in vivo approaches.
Hidalgo-Figueroa S, Ramírez-Espinosa JJ, Estrada-Soto S, Almanza-Pérez JC, Román-Ramos R, Alarcón-Aguilar FJ, Hernández-Rosado JV, Moreno-Díaz H, Díaz-Coutiño D, Navarrete-Vázquez G. Hidalgo-Figueroa S, et al. Chem Biol Drug Des. 2013 Apr;81(4):474-83. doi: 10.1111/cbdd.12102. Epub 2013 Mar 21. Chem Biol Drug Des. 2013. PMID: 23289972
106 results