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Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.
Munday JC, Eze AA, Baker N, Glover L, Clucas C, Aguinaga Andrés D, Natto MJ, Teka IA, McDonald J, Lee RS, Graf FE, Ludin P, Burchmore RJ, Turner CM, Tait A, MacLeod A, Mäser P, Barrett MP, Horn D, De Koning HP. Munday JC, et al. Among authors: natto mj. J Antimicrob Chemother. 2014 Mar;69(3):651-63. doi: 10.1093/jac/dkt442. Epub 2013 Nov 13. J Antimicrob Chemother. 2014. PMID: 24235095 Free PMC article.
In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27.
Acosta-Reyes FJ, Dardonville C, de Koning HP, Natto M, Subirana JA, Campos JL. Acosta-Reyes FJ, et al. Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1614-21. doi: 10.1107/S139900471400697X. Epub 2014 May 24. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24914972 Free PMC article.
Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents.
Khandazhinskaya AL, Matyugina ES, Solyev PN, Wilkinson M, Buckheit KW, Buckheit RW Jr, Chernousova LN, Smirnova TG, Andreevskaya SN, Alzahrani KJ, Natto MJ, Kochetkov SN, de Koning HP, Seley-Radtke KL. Khandazhinskaya AL, et al. Among authors: natto mj. Molecules. 2019 Sep 21;24(19):3433. doi: 10.3390/molecules24193433. Molecules. 2019. PMID: 31546633 Free PMC article.
Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis.
Natto MJ, Hulpia F, Kalkman ER, Baillie S, Alhejeli A, Miyamoto Y, Eckmann L, Van Calenbergh S, de Koning HP. Natto MJ, et al. ACS Infect Dis. 2021 Jun 11;7(6):1752-1764. doi: 10.1021/acsinfecdis.1c00075. Epub 2021 May 11. ACS Infect Dis. 2021. PMID: 33974405 Free PMC article.
17 results