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Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
Nature. 2020 Oct;586(7828):292-298. doi: 10.1038/s41586-020-2769-8. Epub 2020 Sep 30.
Nature. 2020.
PMID: 32999459
Free PMC article.
Neuronal enhancers are hotspots for DNA single-strand break repair.
Wu W, Hill SE, Nathan WJ, Paiano J, Callen E, Wang D, Shinoda K, van Wietmarschen N, Colón-Mercado JM, Zong D, De Pace R, Shih HY, Coon S, Parsadanian M, Pavani R, Hanzlikova H, Park S, Jung SK, McHugh PJ, Canela A, Chen C, Casellas R, Caldecott KW, Ward ME, Nussenzweig A.
Wu W, et al. Among authors: nathan wj.
Nature. 2021 May;593(7859):440-444. doi: 10.1038/s41586-021-03468-5. Epub 2021 Mar 25.
Nature. 2021.
PMID: 33767446
Free PMC article.
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The WRN helicase: resolving a new target in microsatellite unstable cancers.
van Wietmarschen N, Nathan WJ, Nussenzweig A.
van Wietmarschen N, et al. Among authors: nathan wj.
Curr Opin Genet Dev. 2021 Dec;71:34-38. doi: 10.1016/j.gde.2021.06.014. Epub 2021 Jul 17.
Curr Opin Genet Dev. 2021.
PMID: 34284257
Review.
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S1-END-seq reveals DNA secondary structures in human cells.
Matos-Rodrigues G, van Wietmarschen N, Wu W, Tripathi V, Koussa NC, Pavani R, Nathan WJ, Callen E, Belinky F, Mohammed A, Napierala M, Usdin K, Ansari AZ, Mirkin SM, Nussenzweig A.
Matos-Rodrigues G, et al. Among authors: nathan wj.
Mol Cell. 2022 Oct 6;82(19):3538-3552.e5. doi: 10.1016/j.molcel.2022.08.007. Epub 2022 Sep 7.
Mol Cell. 2022.
PMID: 36075220
Free PMC article.
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Active DNA demethylation promotes cell fate specification and the DNA damage response.
Wang D, Wu W, Callen E, Pavani R, Zolnerowich N, Kodali S, Zong D, Wong N, Noriega S, Nathan WJ, Matos-Rodrigues G, Chari R, Kruhlak MJ, Livak F, Ward M, Caldecott K, Di Stefano B, Nussenzweig A.
Wang D, et al. Among authors: nathan wj.
Science. 2022 Dec 2;378(6623):983-989. doi: 10.1126/science.add9838. Epub 2022 Dec 1.
Science. 2022.
PMID: 36454826
Free PMC article.
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Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence.
Saayman X, Graham E, Nathan WJ, Nussenzweig A, Esashi F.
Saayman X, et al. Among authors: nathan wj.
Mol Cell. 2023 Feb 16;83(4):523-538.e7. doi: 10.1016/j.molcel.2023.01.004. Epub 2023 Jan 25.
Mol Cell. 2023.
PMID: 36702125
Free PMC article.
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Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.
Liu G, Park SH, Imbesi M, Nathan WJ, Zou X, Zhu Y, Jiang H, Parisiadou L, Gius D.
Liu G, et al. Among authors: nathan wj.
Antioxid Redox Signal. 2017 May 20;26(15):849-863. doi: 10.1089/ars.2016.6662. Epub 2016 Sep 8.
Antioxid Redox Signal. 2017.
PMID: 27460777
Free PMC article.
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