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Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Kamphorst AO, Wieland A, Nasti T, Yang S, Zhang R, Barber DL, Konieczny BT, Daugherty CZ, Koenig L, Yu K, Sica GL, Sharpe AH, Freeman GJ, Blazar BR, Turka LA, Owonikoko TK, Pillai RN, Ramalingam SS, Araki K, Ahmed R. Kamphorst AO, et al. Among authors: nasti t. Science. 2017 Mar 31;355(6332):1423-1427. doi: 10.1126/science.aaf0683. Epub 2017 Mar 9. Science. 2017. PMID: 28280249 Free PMC article.
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Im SJ, Hashimoto M, Gerner MY, Lee J, Kissick HT, Burger MC, Shan Q, Hale JS, Lee J, Nasti TH, Sharpe AH, Freeman GJ, Germain RN, Nakaya HI, Xue HH, Ahmed R. Im SJ, et al. Among authors: nasti th. Nature. 2016 Sep 15;537(7620):417-421. doi: 10.1038/nature19330. Epub 2016 Aug 2. Nature. 2016. PMID: 27501248 Free PMC article.
Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients.
Kamphorst AO, Pillai RN, Yang S, Nasti TH, Akondy RS, Wieland A, Sica GL, Yu K, Koenig L, Patel NT, Behera M, Wu H, McCausland M, Chen Z, Zhang C, Khuri FR, Owonikoko TK, Ahmed R, Ramalingam SS. Kamphorst AO, et al. Among authors: nasti th. Proc Natl Acad Sci U S A. 2017 May 9;114(19):4993-4998. doi: 10.1073/pnas.1705327114. Epub 2017 Apr 26. Proc Natl Acad Sci U S A. 2017. PMID: 28446615 Free PMC article.
Myocarditis With Radiotherapy and Immunotherapy in Multiple Myeloma.
Chang A, Nasti TH, Khan MK, Parashar S, Kaufman JL, Boise LH, Lonial S, Ahmed R, Nooka AK. Chang A, et al. J Oncol Pract. 2018 Sep;14(9):561-564. doi: 10.1200/JOP.18.00208. Epub 2018 Jul 13. J Oncol Pract. 2018. PMID: 30004825 No abstract available.
T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient.
Wieland A, Kamphorst AO, Adsay NV, Masor JJ, Sarmiento J, Nasti TH, Darko S, Douek DC, Xue Y, Curran WJ, Lawson DH, Ahmed R. Wieland A, et al. Cancer Immunol Immunother. 2018 Nov;67(11):1767-1776. doi: 10.1007/s00262-018-2228-7. Epub 2018 Aug 22. Cancer Immunol Immunother. 2018. PMID: 30167863 Free PMC article.
Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with Coronavirus Disease 2019-Related Pneumonia.
Hess CB, Nasti TH, Dhere VR, Kleber TJ, Switchenko JM, Buchwald ZS, Stokes WA, Weinberg BD, Rouphael N, Steinberg JP, Godette KD, Murphy DJ, Ahmed R, Curran WJ Jr, Khan MK. Hess CB, et al. Int J Radiat Oncol Biol Phys. 2021 Mar 15;109(4):867-879. doi: 10.1016/j.ijrobp.2020.12.011. Epub 2020 Dec 16. Int J Radiat Oncol Biol Phys. 2021. PMID: 33340603 Free PMC article. Clinical Trial.
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