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PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.
Chandrakanthan V, Yeola A, Kwan JC, Oliver RA, Qiao Q, Kang YC, Zarzour P, Beck D, Boelen L, Unnikrishnan A, Villanueva JE, Nunez AC, Knezevic K, Palu C, Nasrallah R, Carnell M, Macmillan A, Whan R, Yu Y, Hardy P, Grey ST, Gladbach A, Delerue F, Ittner L, Mobbs R, Walkley CR, Purton LE, Ward RL, Wong JW, Hesson LB, Walsh W, Pimanda JE. Chandrakanthan V, et al. Among authors: nasrallah r. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):E2306-15. doi: 10.1073/pnas.1518244113. Epub 2016 Apr 4. Proc Natl Acad Sci U S A. 2016. PMID: 27044077 Free PMC article.
Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes.
Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, Roychoudhuri R, Paul F, Klippert J, Hammes A, Willnow T, Göttgens B, Dzierzak E, Zon LI, Lacaud G, Kouskoff V, Pimanda JE. Nasrallah R, et al. Blood. 2016 Oct 13;128(15):1928-1939. doi: 10.1182/blood-2016-02-697870. Epub 2016 Aug 23. Blood. 2016. PMID: 27554085 Free PMC article.
A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells.
Nasrallah R, Imianowski CJ, Bossini-Castillo L, Grant FM, Dogan M, Placek L, Kozhaya L, Kuo P, Sadiyah F, Whiteside SK, Mumbach MR, Glinos D, Vardaka P, Whyte CE, Lozano T, Fujita T, Fujii H, Liston A, Andrews S, Cozzani A, Yang J, Mitra S, Lugli E, Chang HY, Unutmaz D, Trynka G, Roychoudhuri R. Nasrallah R, et al. Nature. 2020 Jul;583(7816):447-452. doi: 10.1038/s41586-020-2296-7. Epub 2020 May 13. Nature. 2020. PMID: 32499651 Free PMC article.
CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function.
Whiteside SK, Grant FM, Gyori DS, Conti AG, Imianowski CJ, Kuo P, Nasrallah R, Sadiyah F, Lira SA, Tacke F, Eil RL, Burton OT, Dooley J, Liston A, Okkenhaug K, Yang J, Roychoudhuri R. Whiteside SK, et al. Among authors: nasrallah r. Immunology. 2021 Aug;163(4):512-520. doi: 10.1111/imm.13337. Epub 2021 May 9. Immunology. 2021. PMID: 33838058 Free PMC article.
BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression.
Grant FM, Yang J, Nasrallah R, Clarke J, Sadiyah F, Whiteside SK, Imianowski CJ, Kuo P, Vardaka P, Todorov T, Zandhuis N, Patrascan I, Tough DF, Kometani K, Eil R, Kurosaki T, Okkenhaug K, Roychoudhuri R. Grant FM, et al. Among authors: nasrallah r. J Exp Med. 2020 Sep 7;217(9):e20190711. doi: 10.1084/jem.20190711. J Exp Med. 2020. PMID: 32515782 Free PMC article.
TCR-induced FOXP3 expression by CD8+ T cells impairs their anti-tumor activity.
Lozano T, Conde E, Martín-Otal C, Navarro F, Lasarte-Cia A, Nasrallah R, Alignani D, Gorraiz M, Sarobe P, Romero JP, Vilas A, Roychoudhuri R, Hervás-Stubbs S, Casares N, Lasarte JJ. Lozano T, et al. Among authors: nasrallah r. Cancer Lett. 2022 Mar 1;528:45-58. doi: 10.1016/j.canlet.2021.12.030. Epub 2021 Dec 29. Cancer Lett. 2022. PMID: 34973390
Comparative analysis of hypertensive nephrosclerosis in animal models of hypertension and its relevance to human pathology. Glomerulopathy.
Gutsol AA, Blanco P, Hale TM, Thibodeau JF, Holterman CE, Nasrallah R, Correa JWN, Afanasiev SA, Touyz RM, Kennedy CRJ, Burger D, Hébert RL, Burns KD. Gutsol AA, et al. Among authors: nasrallah r. PLoS One. 2022 Feb 17;17(2):e0264136. doi: 10.1371/journal.pone.0264136. eCollection 2022. PLoS One. 2022. PMID: 35176122 Free PMC article.
48 results