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The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection.
Lécuyer D, Nardacci R, Tannous D, Gutierrez-Mateyron E, Deva Nathan A, Subra F, Di Primio C, Quaranta P, Petit V, Richetta C, Mostefa-Kara A, Del Nonno F, Falasca L, Marlin R, Maisonnasse P, Delahousse J, Pascaud J, Deprez E, Naigeon M, Chaput N, Paci A, Saada V, Ghez D, Mariette X, Costa M, Pistello M, Allouch A, Delelis O, Piacentini M, Le Grand R, Perfettini JL. Lécuyer D, et al. Among authors: nardacci r. Front Immunol. 2023 Oct 18;14:1270081. doi: 10.3389/fimmu.2023.1270081. eCollection 2023. Front Immunol. 2023. PMID: 37920468 Free PMC article.
Pleural Mesothelial Cells Modulate the Inflammatory/Profibrotic Response During SARS-CoV-2 Infection.
Matusali G, Trionfetti F, Bordoni V, Nardacci R, Falasca L, Colombo D, Terri M, Montaldo C, Castilletti C, Mariotti D, Del Nonno F, Capobianchi MR, Agrati C, Tripodi M, Strippoli R. Matusali G, et al. Among authors: nardacci r. Front Mol Biosci. 2021 Nov 26;8:752616. doi: 10.3389/fmolb.2021.752616. eCollection 2021. Front Mol Biosci. 2021. PMID: 34901152 Free PMC article.
HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry.
Paoletti A, Allouch A, Caillet M, Saïdi H, Subra F, Nardacci R, Wu Q, Muradova Z, Voisin L, Raza SQ, Law F, Thoreau M, Dakhli H, Delelis O, Poirier-Beaudouin B, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Saez-Cirion A, Pancino G, Ojcius DM, Solary E, Deutsch E, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL. Paoletti A, et al. Among authors: nardacci r. Cell Rep. 2019 Sep 24;28(13):3381-3394.e7. doi: 10.1016/j.celrep.2019.02.095. Cell Rep. 2019. PMID: 31553908 Free article.
SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends.
Allouch A, Di Primio C, Paoletti A, Lê-Bury G, Subra F, Quercioli V, Nardacci R, David A, Saïdi H, Cereseto A, Ojcius DM, Montagnac G, Niedergang F, Pancino G, Saez-Cirion A, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL. Allouch A, et al. Among authors: nardacci r. Cell Death Differ. 2020 Dec;27(12):3243-3257. doi: 10.1038/s41418-020-0573-5. Epub 2020 Jun 8. Cell Death Differ. 2020. PMID: 32514048 Free PMC article.
Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis.
Nardacci R, Colavita F, Castilletti C, Lapa D, Matusali G, Meschi S, Del Nonno F, Colombo D, Capobianchi MR, Zumla A, Ippolito G, Piacentini M, Falasca L. Nardacci R, et al. Cell Death Dis. 2021 Mar 12;12(3):263. doi: 10.1038/s41419-021-03527-9. Cell Death Dis. 2021. PMID: 33712574 Free PMC article.
Transglutaminase 2 Regulates Innate Immunity by Modulating the STING/TBK1/IRF3 Axis.
Occhigrossi L, Rossin F, D'Eletto M, Farrace MG, Ciccosanti F, Petrone L, Sacchi A, Nardacci R, Falasca L, Del Nonno F, Palucci I, Smirnov E, Barlev N, Agrati C, Goletti D, Delogu G, Fimia GM, Piacentini M. Occhigrossi L, et al. Among authors: nardacci r. J Immunol. 2021 May 15;206(10):2420-2429. doi: 10.4049/jimmunol.2001122. Epub 2021 May 3. J Immunol. 2021. PMID: 33941660
May macroglossia in COVID-19 be related not only to angioedema?
Colombo D, Del Nonno F, Nardacci R, Falasca L. Colombo D, et al. Among authors: nardacci r. J Infect Public Health. 2022 Jan;15(1):112-115. doi: 10.1016/j.jiph.2021.10.026. Epub 2021 Nov 1. J Infect Public Health. 2022. PMID: 34764043 Free PMC article.
The STING/TBK1/IRF3/IFN type I pathway is defective in cystic fibrosis.
Occhigrossi L, Rossin F, Villella VR, Esposito S, Abbate C, D'Eletto M, Farrace MG, Tosco A, Nardacci R, Fimia GM, Raia V, Piacentini M. Occhigrossi L, et al. Among authors: nardacci r. Front Immunol. 2023 Feb 27;14:1093212. doi: 10.3389/fimmu.2023.1093212. eCollection 2023. Front Immunol. 2023. PMID: 36923406 Free PMC article.
80 results