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Off-target platelet activation in macaques unique to a therapeutic monoclonal antibody.
Santostefano MJ, Kirchner J, Vissinga C, Fort M, Lear S, Pan WJ, Prince PJ, Hensley KM, Tran D, Rock D, Vargas HM, Narayanan P, Jawando R, Rees W, Reindel JF, Reynhardt K, Everds N. Santostefano MJ, et al. Among authors: narayanan p. Toxicol Pathol. 2012 Aug;40(6):899-917. doi: 10.1177/0192623312444029. Epub 2012 May 2. Toxicol Pathol. 2012. PMID: 22552394
Unexpected thrombocytopenia and anemia in cynomolgus monkeys induced by a therapeutic human monoclonal antibody.
Everds N, Li N, Bailey K, Fort M, Stevenson R, Jawando R, Salyers K, Jawa V, Narayanan P, Stevens E, He C, Nguyen MP, Tran S, Doyle N, Poitout-Belissent F, Jolette J, Xu C, Sprugel K. Everds N, et al. Among authors: narayanan p. Toxicol Pathol. 2013;41(7):951-69. doi: 10.1177/0192623312474727. Epub 2013 Mar 7. Toxicol Pathol. 2013. PMID: 23475561
605 results