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Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.
Fustin JM, Kojima R, Itoh K, Chang HY, Ye S, Zhuang B, Oji A, Gibo S, Narasimamurthy R, Virshup D, Kurosawa G, Doi M, Manabe I, Ishihama Y, Ikawa M, Okamura H. Fustin JM, et al. Among authors: narasimamurthy r. Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):5980-5985. doi: 10.1073/pnas.1721371115. Epub 2018 May 21. Proc Natl Acad Sci U S A. 2018. PMID: 29784786 Free PMC article.
CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.
Narasimamurthy R, Hunt SR, Lu Y, Fustin JM, Okamura H, Partch CL, Forger DB, Kim JK, Virshup DM. Narasimamurthy R, et al. Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):5986-5991. doi: 10.1073/pnas.1721076115. Epub 2018 May 21. Proc Natl Acad Sci U S A. 2018. PMID: 29784789 Free PMC article.
Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch.
Masuda S, Narasimamurthy R, Yoshitane H, Kim JK, Fukada Y, Virshup DM. Masuda S, et al. Among authors: narasimamurthy r. Proc Natl Acad Sci U S A. 2020 May 19;117(20):10888-10896. doi: 10.1073/pnas.2000266117. Epub 2020 Apr 30. Proc Natl Acad Sci U S A. 2020. PMID: 32354999 Free PMC article.
15 results