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Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis.
Millet V, Gensollen T, Maltese M, Serrero M, Lesavre N, Bourges C, Pitaval C, Cadra S, Chasson L, Vu Man TP, Masse M, Martinez-Garcia JJ, Tranchida F, Shintu L, Mostert K, Strauss E, Lepage P, Chamaillard M, Broggi A, Peyrin-Biroulet L, Grimaud JC, Naquet P, Galland F. Millet V, et al. Among authors: naquet p. Gut. 2023 Jun;72(6):1115-1128. doi: 10.1136/gutjnl-2021-325792. Epub 2022 Sep 29. Gut. 2023. PMID: 36175116
Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress.
Berruyer C, Martin FM, Castellano R, Macone A, Malergue F, Garrido-Urbani S, Millet V, Imbert J, Duprè S, Pitari G, Naquet P, Galland F. Berruyer C, et al. Among authors: naquet p. Mol Cell Biol. 2004 Aug;24(16):7214-24. doi: 10.1128/MCB.24.16.7214-7224.2004. Mol Cell Biol. 2004. PMID: 15282320 Free PMC article.
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