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DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2.
Kaarijärvi R, Kaljunen H, Nappi L, Fazli L, Kung SHY, Hartikainen JM, Paakinaho V, Capra J, Rilla K, Malinen M, Mäkinen PI, Ylä-Herttuala S, Zoubeidi A, Wang Y, Gleave ME, Hiltunen M, Ketola K. Kaarijärvi R, et al. Among authors: nappi l. Commun Biol. 2024 Jan 18;7(1):108. doi: 10.1038/s42003-023-05741-x. Commun Biol. 2024. PMID: 38238517 Free PMC article.
Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.
Al Nakouzi N, Wang CK, Beraldi E, Jager W, Ettinger S, Fazli L, Nappi L, Bishop J, Zhang F, Chauchereau A, Loriot Y, Gleave M. Al Nakouzi N, et al. Among authors: nappi l. EMBO Mol Med. 2016 Jul 1;8(7):761-78. doi: 10.15252/emmm.201506059. Print 2016 Jul. EMBO Mol Med. 2016. PMID: 27198502 Free PMC article.
Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models.
Nappi L, Aguda AH, Nakouzi NA, Lelj-Garolla B, Beraldi E, Lallous N, Thi M, Moore S, Fazli L, Battsogt D, Stief S, Ban F, Nguyen NT, Saxena N, Dueva E, Zhang F, Yamazaki T, Zoubeidi A, Cherkasov A, Brayer GD, Gleave M. Nappi L, et al. J Clin Invest. 2020 Feb 3;130(2):699-714. doi: 10.1172/JCI130819. J Clin Invest. 2020. PMID: 31845908 Free PMC article.
LIN28B promotes the development of neuroendocrine prostate cancer.
Lovnicki J, Gan Y, Feng T, Li Y, Xie N, Ho CH, Lee AR, Chen X, Nappi L, Han B, Fazli L, Huang J, Gleave ME, Dong X. Lovnicki J, et al. Among authors: nappi l. J Clin Invest. 2020 Oct 1;130(10):5338-5348. doi: 10.1172/JCI135373. J Clin Invest. 2020. PMID: 32634132 Free PMC article.
241 results