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Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Sas-Chen A, Thomas JM, Matzov D, Taoka M, Nance KD, Nir R, Bryson KM, Shachar R, Liman GLS, Burkhart BW, Gamage ST, Nobe Y, Briney CA, Levy MJ, Fuchs RT, Robb GB, Hartmann J, Sharma S, Lin Q, Florens L, Washburn MP, Isobe T, Santangelo TJ, Shalev-Benami M, Meier JL, Schwartz S. Sas-Chen A, et al. Among authors: nance kd. Nature. 2020 Jul;583(7817):638-643. doi: 10.1038/s41586-020-2418-2. Epub 2020 Jun 17. Nature. 2020. PMID: 32555463 Free PMC article.
A Chemical Signature for Cytidine Acetylation in RNA.
Thomas JM, Briney CA, Nance KD, Lopez JE, Thorpe AL, Fox SD, Bortolin-Cavaille ML, Sas-Chen A, Arango D, Oberdoerffer S, Cavaille J, Andresson T, Meier JL. Thomas JM, et al. Among authors: nance kd. J Am Chem Soc. 2018 Oct 10;140(40):12667-12670. doi: 10.1021/jacs.8b06636. Epub 2018 Sep 25. J Am Chem Soc. 2018. PMID: 30252461 Free PMC article.
Cytidine acetylation yields a hypoinflammatory synthetic messenger RNA.
Nance KD, Gamage ST, Alam MM, Yang A, Levy MJ, Link CN, Florens L, Washburn MP, Gu S, Oppenheim JJ, Meier JL. Nance KD, et al. Cell Chem Biol. 2022 Feb 17;29(2):312-320.e7. doi: 10.1016/j.chembiol.2021.07.003. Epub 2021 Aug 25. Cell Chem Biol. 2022. PMID: 35180432 Free PMC article.
Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.
Shrimp JH, Jing Y, Gamage ST, Nelson KM, Han J, Bryson KM, Montgomery DC, Thomas JM, Nance KD, Sharma S, Fox SD, Andressen T, Sinclair WR, Wu H, Allali-Hassani A, Senisterra G, Vedadi M, Lafontaine D, Dahlin JL, Marmorstein R, Walters MA, Meier JL. Shrimp JH, et al. Among authors: nance kd. ACS Med Chem Lett. 2020 Jul 27;12(6):887-892. doi: 10.1021/acsmedchemlett.0c00193. eCollection 2021 Jun 10. ACS Med Chem Lett. 2020. PMID: 34141066 Free PMC article.
A Systems Chemoproteomic Analysis of Acyl-CoA/Protein Interaction Networks.
Levy MJ, Montgomery DC, Sardiu ME, Montano JL, Bergholtz SE, Nance KD, Thorpe AL, Fox SD, Lin Q, Andresson T, Florens L, Washburn MP, Meier JL. Levy MJ, et al. Among authors: nance kd. Cell Chem Biol. 2020 Mar 19;27(3):322-333.e5. doi: 10.1016/j.chembiol.2019.11.011. Epub 2019 Dec 10. Cell Chem Biol. 2020. PMID: 31836350 Free PMC article.
Conditional Covalent Lethality Driven by Oncometabolite Accumulation.
Perez M, Nance KD, Bak DW, Thalalla Gamage S, Najera SS, Conte AN, Linehan WM, Weerapana E, Meier JL. Perez M, et al. Among authors: nance kd. ACS Chem Biol. 2022 Oct 21;17(10):2789-2800. doi: 10.1021/acschembio.2c00384. Epub 2022 Oct 3. ACS Chem Biol. 2022. PMID: 36190452 Free PMC article.
Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia.
Wood MR, Noetzel MJ, Melancon BJ, Poslusney MS, Nance KD, Hurtado MA, Luscombe VB, Weiner RL, Rodriguez AL, Lamsal A, Chang S, Bubser M, Blobaum AL, Engers DW, Niswender CM, Jones CK, Brandon NJ, Wood MW, Duggan ME, Conn PJ, Bridges TM, Lindsley CW. Wood MR, et al. Among authors: nance kd. ACS Med Chem Lett. 2016 Dec 16;8(2):233-238. doi: 10.1021/acsmedchemlett.6b00461. eCollection 2017 Feb 9. ACS Med Chem Lett. 2016. PMID: 28197318 Free PMC article.
25 results