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Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, Ranjan A, Devost D, Namkung Y, Stepniewski TM, Pandey S, Baruah M, Panigrahi B, Sarma P, Yadav MK, Maharana J, Banerjee R, Kawakami K, Inoue A, Selent J, Laporte SA, Hébert TE, Shukla AK. Baidya M, et al. Among authors: namkung y. Nat Commun. 2022 Aug 8;13(1):4634. doi: 10.1038/s41467-022-32386-x. Nat Commun. 2022. PMID: 35941121 Free PMC article.
Standardized Cannabis Smoke Extract Induces Inflammation in Human Lung Fibroblasts.
Aloufi N, Namkung Y, Traboulsi H, Wilson ET, Laporte SA, Kaplan BLF, Ross MK, Nair P, Eidelman DH, Baglole CJ. Aloufi N, et al. Among authors: namkung y. Front Pharmacol. 2022 Mar 28;13:852029. doi: 10.3389/fphar.2022.852029. eCollection 2022. Front Pharmacol. 2022. PMID: 35418857 Free PMC article.
Pharmacological Characterization of the Imipridone Anticancer Drug ONC201 Reveals a Negative Allosteric Mechanism of Action at the D2 Dopamine Receptor.
Free RB, Cuoco CA, Xie B, Namkung Y, Prabhu VV, Willette BKA, Day MM, Sanchez-Soto M, Lane JR, Laporte SA, Shi L, Allen JE, Sibley DR. Free RB, et al. Among authors: namkung y. Mol Pharmacol. 2021 Oct;100(4):372-387. doi: 10.1124/molpharm.121.000336. Epub 2021 Aug 5. Mol Pharmacol. 2021. PMID: 34353882 Free PMC article.
Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen.
Giubilaro J, Schuetz DA, Stepniewski TM, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, Marinier A, Laporte SA. Giubilaro J, et al. Among authors: namkung y. Nat Commun. 2021 Aug 3;12(1):4688. doi: 10.1038/s41467-021-24968-y. Nat Commun. 2021. PMID: 34344896 Free PMC article.
Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR.
Lukasheva V, Devost D, Le Gouill C, Namkung Y, Martin RD, Longpré JM, Amraei M, Shinjo Y, Hogue M, Lagacé M, Breton B, Aoki J, Tanny JC, Laporte SA, Pineyro G, Inoue A, Bouvier M, Hébert TE. Lukasheva V, et al. Among authors: namkung y. Sci Rep. 2020 May 29;10(1):8779. doi: 10.1038/s41598-020-65636-3. Sci Rep. 2020. PMID: 32471984 Free PMC article.
37 results