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Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J Med Chem. 2023 Mar 23;66(6):4059-4085. doi: 10.1021/acs.jmedchem.2c02059. Epub 2023 Mar 7.
J Med Chem. 2023.
PMID: 36882960
A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression.
Takase S, Hiroyama T, Shirai F, Maemoto Y, Nakata A, Arata M, Matsuoka S, Sonoda T, Niwa H, Sato S, Umehara T, Shirouzu M, Nishigaya Y, Sumiya T, Hashimoto N, Namie R, Usui M, Ohishi T, Ohba SI, Kawada M, Hayashi Y, Harada H, Yamaguchi T, Shinkai Y, Nakamura Y, Yoshida M, Ito A.
Takase S, et al. Among authors: namie r.
Nat Commun. 2023 Jan 12;14(1):23. doi: 10.1038/s41467-022-35404-0.
Nat Commun. 2023.
PMID: 36635268
Free PMC article.
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Discovery of Novel Bicyclic Pyrazoles as Potent PIP5K1C Inhibitors.
Ochiai K, Seto S, Yajima M, Namie R, Hashimoto N, Fujita M, Yokoyama A, Suezawa T, Matsui H, Tomizawa S, Ishibashi Y, Tanaka Y, Yajima M, Nagasawa M, Ando N.
Ochiai K, et al. Among authors: namie r.
ACS Med Chem Lett. 2024 Apr 3;15(5):684-690. doi: 10.1021/acsmedchemlett.4c00090. eCollection 2024 May 9.
ACS Med Chem Lett. 2024.
PMID: 38746884
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