Naldini L - Search Results

1

Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress.

Montaldo E, Lusito E, Bianchessi V, Caronni N, Scala S, Basso-Ricci L, Cantaffa C, Masserdotti A, Barilaro M, Barresi S, Genua M, Vittoria FM, Barbiera G, Lazarevic D, Messina C, Xue E, Marktel S, Tresoldi C, Milani R, Ronchi P, Gattillo S, Santoleri L, Di Micco R, Ditadi A, Belfiori G, Aleotti F, Naldini MM, Gentner B, Gardiman E, Tamassia N, Cassatella MA, Hidalgo A, Kwok I, Ng LG, Crippa S, Falconi M, Pettinella F, Scapini P, Naldini L, Ciceri F, Aiuti A, Ostuni R. Montaldo E, et al. Among authors: naldini mm, naldini l. Nat Immunol. 2022 Oct;23(10):1470-1483. doi: 10.1038/s41590-022-01311-1. Epub 2022 Sep 22. Nat Immunol. 2022. PMID: 36138183 Free PMC article.

2

Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

Dupré L, Trifari S, Follenzi A, Marangoni F, Lain de Lera T, Bernad A, Martino S, Tsuchiya S, Bordignon C, Naldini L, Aiuti A, Roncarolo MG. Dupré L, et al. Among authors: naldini l. Mol Ther. 2004 Nov;10(5):903-15. doi: 10.1016/j.ymthe.2004.08.008. Mol Ther. 2004. PMID: 15509508 Free article.

3

Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation.

Dupré L, Marangoni F, Scaramuzza S, Trifari S, Hernández RJ, Aiuti A, Naldini L, Roncarolo MG. Dupré L, et al. Among authors: naldini l. Hum Gene Ther. 2006 Mar;17(3):303-13. doi: 10.1089/hum.2006.17.303. Hum Gene Ther. 2006. PMID: 16544979

4

Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state.

Brown BD, Gentner B, Cantore A, Colleoni S, Amendola M, Zingale A, Baccarini A, Lazzari G, Galli C, Naldini L. Brown BD, et al. Among authors: naldini l. Nat Biotechnol. 2007 Dec;25(12):1457-67. doi: 10.1038/nbt1372. Epub 2007 Nov 16. Nat Biotechnol. 2007. PMID: 18026085

5

Stable knockdown of microRNA in vivo by lentiviral vectors.

Gentner B, Schira G, Giustacchini A, Amendola M, Brown BD, Ponzoni M, Naldini L. Gentner B, et al. Among authors: naldini l. Nat Methods. 2009 Jan;6(1):63-6. doi: 10.1038/nmeth.1277. Epub 2008 Nov 30. Nat Methods. 2009. PMID: 19043411

6

Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform.

Amendola M, Passerini L, Pucci F, Gentner B, Bacchetta R, Naldini L. Amendola M, et al. Among authors: naldini l. Mol Ther. 2009 Jun;17(6):1039-52. doi: 10.1038/mt.2009.48. Epub 2009 Mar 17. Mol Ther. 2009. PMID: 19293777 Free PMC article.

7

Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy.

Cassani B, Montini E, Maruggi G, Ambrosi A, Mirolo M, Selleri S, Biral E, Frugnoli I, Hernandez-Trujillo V, Di Serio C, Roncarolo MG, Naldini L, Mavilio F, Aiuti A. Cassani B, et al. Among authors: naldini l. Blood. 2009 Oct 22;114(17):3546-56. doi: 10.1182/blood-2009-02-202085. Epub 2009 Aug 3. Blood. 2009. PMID: 19652199 Free article. Clinical Trial.

8

The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche.

Visigalli I, Ungari S, Martino S, Park H, Cesani M, Gentner B, Sergi Sergi L, Orlacchio A, Naldini L, Biffi A. Visigalli I, et al. Among authors: naldini l. Blood. 2010 Sep 16;116(11):1857-66. doi: 10.1182/blood-2009-12-256461. Epub 2010 May 28. Blood. 2010. PMID: 20511539 Free PMC article.

9

Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.

Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, Berti A, Politi LS, Gentner B, Brown JL, Naldini L, De Palma M. Mazzieri R, et al. Among authors: naldini l. Cancer Cell. 2011 Apr 12;19(4):512-26. doi: 10.1016/j.ccr.2011.02.005. Cancer Cell. 2011. PMID: 21481792 Free article.

10

Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome.

Bosticardo M, Draghici E, Schena F, Sauer AV, Fontana E, Castiello MC, Catucci M, Locci M, Naldini L, Aiuti A, Roncarolo MG, Poliani PL, Traggiai E, Villa A. Bosticardo M, et al. Among authors: naldini l. J Allergy Clin Immunol. 2011 Jun;127(6):1376-84.e5. doi: 10.1016/j.jaci.2011.03.030. Epub 2011 Apr 29. J Allergy Clin Immunol. 2011. PMID: 21531013

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