Nakauchi Y - Search Results

1

Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal Vulnerability.

Thomas D, Wu M, Nakauchi Y, Zheng M, Thompson-Peach CAL, Lim K, Landberg N, Köhnke T, Robinson N, Kaur S, Kutyna M, Stafford M, Hiwase D, Reinisch A, Peltz G, Majeti R. Thomas D, et al. Among authors: nakauchi y. Cancer Discov. 2023 Feb 6;13(2):496-515. doi: 10.1158/2159-8290.CD-21-0218. Cancer Discov. 2023. PMID: 36355448 Free PMC article.

2

Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion.

Nishimura T, Hsu I, Martinez-Krams DC, Nakauchi Y, Majeti R, Yamazaki S, Nakauchi H, Wilkinson AC. Nishimura T, et al. Among authors: nakauchi y, nakauchi h. Exp Hematol. 2019 Dec;80:16-20. doi: 10.1016/j.exphem.2019.11.007. Epub 2019 Dec 23. Exp Hematol. 2019. PMID: 31874780 Free PMC article.

3

Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2.

Dutta R, Zhang TY, Köhnke T, Thomas D, Linde M, Gars E, Stafford M, Kaur S, Nakauchi Y, Yin R, Azizi A, Narla A, Majeti R. Dutta R, et al. Among authors: nakauchi y. J Clin Invest. 2020 Apr 1;130(4):1843-1849. doi: 10.1172/JCI133344. J Clin Invest. 2020. PMID: 31895700 Free PMC article.

4

Integrated analysis of patient samples identifies biomarkers for venetoclax efficacy and combination strategies in acute myeloid leukemia.

Zhang H, Nakauchi Y, Köhnke T, Stafford M, Bottomly D, Thomas R, Wilmot B, McWeeney SK, Majeti R, Tyner JW. Zhang H, et al. Among authors: nakauchi y. Nat Cancer. 2020 Aug;1(8):826-839. doi: 10.1038/s43018-020-0103-x. Epub 2020 Aug 18. Nat Cancer. 2020. PMID: 33123685 Free PMC article.

5

The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia.

Nakauchi Y, Azizi A, Thomas D, Corces MR, Reinisch A, Sharma R, Cruz Hernandez D, Köhnke T, Karigane D, Fan A, Martinez-Krams D, Stafford M, Kaur S, Dutta R, Phan P, Ediriwickrema A, McCarthy E, Ning Y, Phillips T, Ellison CK, Guler GD, Bergamaschi A, Ku CJ, Levy S, Majeti R. Nakauchi Y, et al. Blood Cancer Discov. 2022 Jul 6;3(4):346-367. doi: 10.1158/2643-3230.BCD-21-0143. Blood Cancer Discov. 2022. PMID: 35532363 Free PMC article.

6

Reengineering Ponatinib to Minimize Cardiovascular Toxicity.

Hnatiuk AP, Bruyneel AAN, Tailor D, Pandrala M, Dheeraj A, Li W, Serrano R, Feyen DAM, Vu MM, Amatya P, Gupta S, Nakauchi Y, Morgado I, Wiebking V, Liao R, Porteus MH, Majeti R, Malhotra SV, Mercola M. Hnatiuk AP, et al. Among authors: nakauchi y. Cancer Res. 2022 Aug 3;82(15):2777-2791. doi: 10.1158/0008-5472.CAN-21-3652. Cancer Res. 2022. PMID: 35763671 Free PMC article.

7

RUNX1 loss renders hematopoietic and leukemic cells dependent on IL-3 and sensitive to JAK inhibition.

Fan AC, Nakauchi Y, Bai L, Azizi A, Nuno KA, Zhao F, Köhnke T, Karigane D, Cruz-Hernandez D, Reinisch A, Khatri P, Majeti R. Fan AC, et al. Among authors: nakauchi y. J Clin Invest. 2023 Oct 2;133(19):e167053. doi: 10.1172/JCI167053. J Clin Invest. 2023. PMID: 37581927 Free PMC article.

8

Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis.

Nakauchi Y, Ediriwickrema A, Martinez-Krams D, Zhao F, Rangavajhula A, Karigane D, Majeti R. Nakauchi Y, et al. J Vis Exp. 2023 Nov 10;(201). doi: 10.3791/65874. J Vis Exp. 2023. PMID: 38009738

9

IDH1-mutant preleukemic hematopoietic stem cells can be eliminated by inhibition of oxidative phosphorylation.

Landberg N, Köhnke T, Feng Y, Nakauchi Y, Fan AC, Linde MH, Karigane D, Lim K, Sinha R, Malcovati L, Thomas D, Majeti R. Landberg N, et al. Among authors: nakauchi y. Blood Cancer Discov. 2023 Dec 13;5(2):114-31. doi: 10.1158/2643-3230.BCD-23-0195. Online ahead of print. Blood Cancer Discov. 2023. PMID: 38091010

10

IDH1-Mutant Preleukemic Hematopoietic Stem Cells Can Be Eliminated by Inhibition of Oxidative Phosphorylation.

Landberg N, Köhnke T, Feng Y, Nakauchi Y, Fan AC, Linde MH, Karigane D, Lim K, Sinha R, Malcovati L, Thomas D, Majeti R. Landberg N, et al. Among authors: nakauchi y. Blood Cancer Discov. 2024 Jan 23:OF1-OF18. doi: 10.1158/2643-3230.BCD-23-0195. Online ahead of print. Blood Cancer Discov. 2024. PMID: 38261864

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