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Intestinal Atp8b1 dysfunction causes hepatic choline deficiency and steatohepatitis.
Tamura R, Sabu Y, Mizuno T, Mizuno S, Nakano S, Suzuki M, Abukawa D, Kaji S, Azuma Y, Inui A, Okamoto T, Shimizu S, Fukuda A, Sakamoto S, Kasahara M, Takahashi S, Kusuhara H, Zen Y, Ando T, Hayashi H. Tamura R, et al. Among authors: nakano s. Nat Commun. 2023 Nov 21;14(1):6763. doi: 10.1038/s41467-023-42424-x. Nat Commun. 2023. PMID: 37990006 Free PMC article.
Assessment of ATP8B1 Deficiency in Pediatric Patients With Cholestasis Using Peripheral Blood Monocyte-Derived Macrophages.
Hayashi H, Naoi S, Togawa T, Hirose Y, Kondou H, Hasegawa Y, Abukawa D, Sasaki M, Muroya K, Watanabe S, Nakano S, Minowa K, Inui A, Fukuda A, Kasahara M, Nagasaka H, Bessho K, Suzuki M, Kusuhara H. Hayashi H, et al. Among authors: nakano s. EBioMedicine. 2018 Jan;27:187-199. doi: 10.1016/j.ebiom.2017.10.007. Epub 2017 Oct 7. EBioMedicine. 2018. PMID: 29104077 Free PMC article.
Effect of food on the pharmacokinetics and therapeutic efficacy of 4-phenylbutyrate in progressive familial intrahepatic cholestasis.
Nakano S, Osaka S, Sabu Y, Minowa K, Hirai S, Kondou H, Kimura T, Azuma Y, Watanabe S, Inui A, Bessho K, Nakamura H, Kusano H, Nakazawa A, Tanikawa K, Kage M, Shimizu T, Kusuhara H, Zen Y, Suzuki M, Hayashi H. Nakano S, et al. Sci Rep. 2019 Nov 19;9(1):17075. doi: 10.1038/s41598-019-53628-x. Sci Rep. 2019. PMID: 31745229 Free PMC article.
Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.
Mizutani A, Sabu Y, Naoi S, Ito S, Nakano S, Minowa K, Mizuochi T, Ito K, Abukawa D, Kaji S, Sasaki M, Muroya K, Azuma Y, Watanabe S, Oya Y, Inomata Y, Fukuda A, Kasahara M, Inui A, Takikawa H, Kusuhara H, Bessho K, Suzuki M, Togawa T, Hayashi H. Mizutani A, et al. Among authors: nakano s. Hepatol Commun. 2020 Sep 26;5(1):52-62. doi: 10.1002/hep4.1605. eCollection 2021 Jan. Hepatol Commun. 2020. PMID: 33437900 Free PMC article.
A randomized trial to examine the impact of food on pharmacokinetics of 4-phenylbutyrate and change in amino acid availability after a single oral administration of sodium 4-phenylbutyrarte in healthy volunteers.
Osaka S, Nakano S, Mizuno T, Hiraoka Y, Minowa K, Hirai S, Mizutani A, Sabu Y, Miura Y, Shimizu T, Kusuhara H, Suzuki M, Hayashi H. Osaka S, et al. Among authors: nakano s. Mol Genet Metab. 2021 Apr;132(4):220-226. doi: 10.1016/j.ymgme.2021.02.002. Epub 2021 Feb 23. Mol Genet Metab. 2021. PMID: 33648834 Clinical Trial.
2,650 results