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Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments.
Kumagai S, Koyama S, Itahashi K, Tanegashima T, Lin YT, Togashi Y, Kamada T, Irie T, Okumura G, Kono H, Ito D, Fujii R, Watanabe S, Sai A, Fukuoka S, Sugiyama E, Watanabe G, Owari T, Nishinakamura H, Sugiyama D, Maeda Y, Kawazoe A, Yukami H, Chida K, Ohara Y, Yoshida T, Shinno Y, Takeyasu Y, Shirasawa M, Nakama K, Aokage K, Suzuki J, Ishii G, Kuwata T, Sakamoto N, Kawazu M, Ueno T, Mori T, Yamazaki N, Tsuboi M, Yatabe Y, Kinoshita T, Doi T, Shitara K, Mano H, Nishikawa H. Kumagai S, et al. Among authors: nakama k. Cancer Cell. 2022 Feb 14;40(2):201-218.e9. doi: 10.1016/j.ccell.2022.01.001. Epub 2022 Jan 28. Cancer Cell. 2022. PMID: 35090594 Free article.
The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies.
Kumagai S, Togashi Y, Kamada T, Sugiyama E, Nishinakamura H, Takeuchi Y, Vitaly K, Itahashi K, Maeda Y, Matsui S, Shibahara T, Yamashita Y, Irie T, Tsuge A, Fukuoka S, Kawazoe A, Udagawa H, Kirita K, Aokage K, Ishii G, Kuwata T, Nakama K, Kawazu M, Ueno T, Yamazaki N, Goto K, Tsuboi M, Mano H, Doi T, Shitara K, Nishikawa H. Kumagai S, et al. Among authors: nakama k. Nat Immunol. 2020 Nov;21(11):1346-1358. doi: 10.1038/s41590-020-0769-3. Epub 2020 Aug 31. Nat Immunol. 2020. PMID: 32868929
Efficacy of oral retinoids for keratoacanthoma centrifugum marginatum.
Mizuta H, Takahashi A, Mori T, Namikawa K, Nakano E, Muto Y, Jinnai S, Nakama K, Tsutsui K, Yamazaki N. Mizuta H, et al. Among authors: nakama k. Dermatol Ther. 2020 May;33(3):e13291. doi: 10.1111/dth.13291. Epub 2020 Mar 14. Dermatol Ther. 2020. PMID: 32125740
Case of multiple ectopic extramammary Paget's disease of the trunk.
Tsutsui K, Namikawa K, Mori T, Jinnai S, Nakama K, Ogata D, Takahashi A, Yamazaki N. Tsutsui K, et al. Among authors: nakama k. J Dermatol. 2020 Sep;47(9):e329-e331. doi: 10.1111/1346-8138.15491. Epub 2020 Jul 6. J Dermatol. 2020. PMID: 32632994 No abstract available.
104 results