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Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion.
Hu X, Yasuda T, Yasuda-Yosihara N, Yonemura A, Umemoto T, Nakachi Y, Yamashita K, Semba T, Arima K, Uchihara T, Nishimura A, Bu L, Fu L, Wei F, Zhang J, Tong Y, Wang H, Iwamoto K, Fukuda T, Nakagawa H, Taniguchi K, Miyamoto Y, Baba H, Ishimoto T. Hu X, et al. Among authors: nakagawa h. JHEP Rep. 2023 Aug 23;5(12):100892. doi: 10.1016/j.jhepr.2023.100892. eCollection 2023 Dec. JHEP Rep. 2023. PMID: 37942226 Free PMC article.
Cell fate analysis of zone 3 hepatocytes in liver injury and tumorigenesis.
Kurosaki S, Nakagawa H, Hayata Y, Kawamura S, Matsushita Y, Yamada T, Uchino K, Hayakawa Y, Suzuki N, Hata M, Tsuboi M, Kinoshita H, Tanaka Y, Nakatsuka T, Hirata Y, Tateishi K, Koike K. Kurosaki S, et al. Among authors: nakagawa h. JHEP Rep. 2021 May 27;3(4):100315. doi: 10.1016/j.jhepr.2021.100315. eCollection 2021 Aug. JHEP Rep. 2021. PMID: 34345813 Free PMC article.
Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway.
Kudo Y, Tanaka Y, Tateishi K, Yamamoto K, Yamamoto S, Mohri D, Isomura Y, Seto M, Nakagawa H, Asaoka Y, Tada M, Ohta M, Ijichi H, Hirata Y, Otsuka M, Ikenoue T, Maeda S, Shiina S, Yoshida H, Nakajima O, Kanai F, Omata M, Koike K. Kudo Y, et al. Among authors: nakagawa h. J Hepatol. 2011 Dec;55(6):1400-8. doi: 10.1016/j.jhep.2011.03.025. Epub 2011 May 19. J Hepatol. 2011. PMID: 21703185
Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence.
Soroida Y, Ohkawa R, Nakagawa H, Satoh Y, Yoshida H, Kinoshita H, Tateishi R, Masuzaki R, Enooku K, Shiina S, Sato T, Obi S, Hoshino T, Nagatomo R, Okubo S, Yokota H, Koike K, Yatomi Y, Ikeda H. Soroida Y, et al. Among authors: nakagawa h. J Hepatol. 2012 Aug;57(2):330-6. doi: 10.1016/j.jhep.2012.03.012. Epub 2012 Apr 17. J Hepatol. 2012. PMID: 22521349
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, Shibata W, Akanuma M, Koike K, Karin M, Maeda S. Nakagawa H, et al. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1090-5. doi: 10.1073/pnas.1322731111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395807 Free PMC article.
p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.
Umemura A, He F, Taniguchi K, Nakagawa H, Yamachika S, Font-Burgada J, Zhong Z, Subramaniam S, Raghunandan S, Duran A, Linares JF, Reina-Campos M, Umemura S, Valasek MA, Seki E, Yamaguchi K, Koike K, Itoh Y, Diaz-Meco MT, Moscat J, Karin M. Umemura A, et al. Among authors: nakagawa h. Cancer Cell. 2016 Jun 13;29(6):935-948. doi: 10.1016/j.ccell.2016.04.006. Epub 2016 May 19. Cancer Cell. 2016. PMID: 27211490 Free PMC article.
4,220 results