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Metformin suppresses intestinal polyp growth in ApcMin/+ mice.
Tomimoto A, Endo H, Sugiyama M, Fujisawa T, Hosono K, Takahashi H, Nakajima N, Nagashima Y, Wada K, Nakagama H, Nakajima A. Tomimoto A, et al. Among authors: nakagama h. Cancer Sci. 2008 Nov;99(11):2136-41. doi: 10.1111/j.1349-7006.2008.00933.x. Epub 2008 Sep 18. Cancer Sci. 2008. PMID: 18803638 Free article.
Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties.
Takahashi H, Fujita K, Fujisawa T, Yonemitsu K, Tomimoto A, Ikeda I, Yoneda M, Masuda T, Schaefer K, Saubermann LJ, Shimamura T, Saitoh S, Tachibana M, Wada K, Nakagama H, Nakajima A. Takahashi H, et al. Among authors: nakagama h. Cancer Sci. 2006 Sep;97(9):854-60. doi: 10.1111/j.1349-7006.2006.00250.x. Epub 2006 Jun 29. Cancer Sci. 2006. PMID: 16805824 Free article.
5-aminosalicylic acid given in the remission stage of colitis suppresses colitis-associated cancer in a mouse colitis model.
Ikeda I, Tomimoto A, Wada K, Fujisawa T, Fujita K, Yonemitsu K, Nozaki Y, Endo H, Takahashi H, Yoneda M, Inamori M, Kubota K, Saito S, Nagashima Y, Nakagama H, Nakajima A. Ikeda I, et al. Among authors: nakagama h. Clin Cancer Res. 2007 Nov 1;13(21):6527-31. doi: 10.1158/1078-0432.CCR-07-1208. Clin Cancer Res. 2007. PMID: 17975166
Inhibition of peroxisome proliferator-activated receptor gamma activity suppresses pancreatic cancer cell motility.
Nakajima A, Tomimoto A, Fujita K, Sugiyama M, Takahashi H, Ikeda I, Hosono K, Endo H, Yoneda K, Iida H, Inamori M, Kubota K, Saito S, Nakajima N, Wada K, Nagashima Y, Nakagama H. Nakajima A, et al. Among authors: nakagama h. Cancer Sci. 2008 Oct;99(10):1892-900. doi: 10.1111/j.1349-7006.2008.00904.x. Cancer Sci. 2008. PMID: 19016747 Free article.
Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine.
Fujisawa T, Sugiyama M, Tomimoto A, Wada K, Endo H, Takahashi H, Yoneda K, Yoneda M, Inamori M, Saito S, Terauchi Y, Kadowaki T, Tsuchiya N, Nakagama H, Nakajima A. Fujisawa T, et al. Among authors: nakagama h. J Pharmacol Sci. 2008 Dec;108(4):535-44. doi: 10.1254/jphs.08193fp. Epub 2008 Dec 10. J Pharmacol Sci. 2008. PMID: 19075513 Free article.
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial.
Hosono K, Endo H, Takahashi H, Sugiyama M, Sakai E, Uchiyama T, Suzuki K, Iida H, Sakamoto Y, Yoneda K, Koide T, Tokoro C, Abe Y, Inamori M, Nakagama H, Nakajima A. Hosono K, et al. Among authors: nakagama h. Cancer Prev Res (Phila). 2010 Sep;3(9):1077-83. doi: 10.1158/1940-6207.CAPR-10-0186. Epub 2010 Sep 1. Cancer Prev Res (Phila). 2010. PMID: 20810669 Clinical Trial.
Life style-related diseases of the digestive system: colorectal cancer as a life style-related disease: from carcinogenesis to medical treatment.
Takahashi H, Yoneda K, Tomimoto A, Endo H, Fujisawa T, Iida H, Mawatari H, Nozaki Y, Ikeda T, Akiyama T, Yoneda M, Inamori M, Abe Y, Saito S, Nakajima A, Nakagama H. Takahashi H, et al. Among authors: nakagama h. J Pharmacol Sci. 2007 Oct;105(2):129-32. doi: 10.1254/jphs.fm0070022. Epub 2007 Oct 6. J Pharmacol Sci. 2007. PMID: 17928742 Free article. Review.
Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catenin/T cell factor (TCF) pathway.
Fujisawa T, Nakajima A, Fujisawa N, Takahashi H, Ikeda I, Tomimoto A, Yonemitsu K, Nakajima N, Kudo C, Wada K, Kubota N, Terauchi Y, Kadowaki T, Nakagama H, Blumberg RS. Fujisawa T, et al. Among authors: nakagama h. J Pharmacol Sci. 2008 Apr;106(4):627-38. doi: 10.1254/jphs.fp0071766. Epub 2008 Apr 5. J Pharmacol Sci. 2008. PMID: 18391483 Free article.
285 results