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Preclinical development of a humanized chimeric antigen receptor against B cell maturation antigen for multiple myeloma.
Perez-Amill L, Suñe G, Antoñana-Vildosola A, Castella M, Najjar A, Bonet J, Fernández-Fuentes N, Inogés S, López A, Bueno C, Juan M, Urbano-Ispizua Á, Martín-Antonio B. Perez-Amill L, et al. Among authors: najjar a. Haematologica. 2021 Jan 1;106(1):173-184. doi: 10.3324/haematol.2019.228577. Haematologica. 2021. PMID: 31919085 Free PMC article.
Extracellular NK histones promote immune cell anti-tumor activity by inducing cell clusters through binding to CD138 receptor.
Martín-Antonio B, Suñe G, Najjar A, Perez-Amill L, Antoñana-Vildosola A, Castella M, León S, Velasco-de Andrés M, Lozano F, Lozano E, Bueno C, Estanyol JM, Muñoz-Pinedo C, Robinson SN, Urbano-Ispizua A. Martín-Antonio B, et al. Among authors: najjar a. J Immunother Cancer. 2019 Oct 16;7(1):259. doi: 10.1186/s40425-019-0739-1. J Immunother Cancer. 2019. PMID: 31619273 Free PMC article.
Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking.
Martin-Antonio B, Najjar A, Robinson SN, Chew C, Li S, Yvon E, Thomas MW, Mc Niece I, Orlowski R, Muñoz-Pinedo C, Bueno C, Menendez P, Fernández de Larrea C, Urbano-Ispizua A, Shpall EJ, Shah N. Martin-Antonio B, et al. Among authors: najjar a. Cell Death Differ. 2015 Jan;22(1):96-107. doi: 10.1038/cdd.2014.120. Epub 2014 Aug 29. Cell Death Differ. 2015. PMID: 25168239 Free PMC article.
Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.
Shah N, Martin-Antonio B, Yang H, Ku S, Lee DA, Cooper LJ, Decker WK, Li S, Robinson SN, Sekine T, Parmar S, Gribben J, Wang M, Rezvani K, Yvon E, Najjar A, Burks J, Kaur I, Champlin RE, Bollard CM, Shpall EJ. Shah N, et al. Among authors: najjar a. PLoS One. 2013 Oct 18;8(10):e76781. doi: 10.1371/journal.pone.0076781. eCollection 2013. PLoS One. 2013. PMID: 24204673 Free PMC article.
Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment.
Robinson SN, Thomas MW, Simmons PJ, Lu J, Yang H, Parmar S, Liu X, Shah N, Martín-Antonio B, Bollard C, Dotti G, Savoldo B, Cooper LJ, Najjar A, Rezvani K, Kaur I, McNiece IK, Champlin RE, Miller LP, Zweidler-McKay PA, Shpall EJ. Robinson SN, et al. Among authors: najjar a. Cytotherapy. 2014 Jan;16(1):84-9. doi: 10.1016/j.jcyt.2013.07.003. Epub 2013 Oct 1. Cytotherapy. 2014. PMID: 24094497 Free PMC article.
Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells.
Hurton LV, Singh H, Najjar AM, Switzer KC, Mi T, Maiti S, Olivares S, Rabinovich B, Huls H, Forget MA, Datar V, Kebriaei P, Lee DA, Champlin RE, Cooper LJ. Hurton LV, et al. Among authors: najjar am. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7788-E7797. doi: 10.1073/pnas.1610544113. Epub 2016 Nov 14. Proc Natl Acad Sci U S A. 2016. PMID: 27849617 Free PMC article.
Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic melanoma.
Saberian C, Amaria RN, Najjar AM, Radvanyi LG, Haymaker CL, Forget MA, Bassett RL, Faria SC, Glitza IC, Alvarez E, Parshottam S, Prieto V, Lizée G, Wong MK, McQuade JL, Diab A, Yee C, Tawbi HA, Patel S, Shpall EJ, Davies MA, Hwu P, Bernatchez C. Saberian C, et al. Among authors: najjar am. J Immunother Cancer. 2021 May;9(5):e002449. doi: 10.1136/jitc-2021-002449. J Immunother Cancer. 2021. PMID: 34021033 Free PMC article. Clinical Trial.
263 results