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Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis.
Benitz S, Straub T, Mahajan UM, Mutter J, Czemmel S, Unruh T, Wingerath B, Deubler S, Fahr L, Cheng T, Nahnsen S, Bruns P, Kong B, Raulefs S, Ceyhan GO, Mayerle J, Steiger K, Esposito I, Kleeff J, Michalski CW, Regel I. Benitz S, et al. Among authors: nahnsen s. Gut. 2019 Nov;68(11):2007-2018. doi: 10.1136/gutjnl-2018-317208. Epub 2019 Apr 6. Gut. 2019. PMID: 30954952
qPortal: A platform for data-driven biomedical research.
Mohr C, Friedrich A, Wojnar D, Kenar E, Polatkan AC, Codrea MC, Czemmel S, Kohlbacher O, Nahnsen S. Mohr C, et al. Among authors: nahnsen s. PLoS One. 2018 Jan 19;13(1):e0191603. doi: 10.1371/journal.pone.0191603. eCollection 2018. PLoS One. 2018. PMID: 29352322 Free PMC article.
Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.
Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP, Vogel M, Schoonjans K, Lautwein T, Köhrer K, Häussinger D, Luedde T, Heikenwalder M, Keitel V. Reich M, et al. Among authors: nahnsen s. J Hepatol. 2021 Sep;75(3):634-646. doi: 10.1016/j.jhep.2021.03.029. Epub 2021 Apr 17. J Hepatol. 2021. PMID: 33872692 Free article.
Experimental glioma with high bHLH expression harbor increased replicative stress and are sensitive toward ATR inhibition.
Koch MS, Czemmel S, Lennartz F, Beyeler S, Rajaraman S, Przystal JM, Govindarajan P, Canjuga D, Neumann M, Rizzu P, Zwirner S, Hoetker MS, Zender L, Walter B, Tatagiba M, Raineteau O, Heutink P, Nahnsen S, Tabatabai G. Koch MS, et al. Among authors: nahnsen s. Neurooncol Adv. 2020 Sep 10;2(1):vdaa115. doi: 10.1093/noajnl/vdaa115. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33134924 Free PMC article.
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma.
Löffler MW, Mohr C, Bichmann L, Freudenmann LK, Walzer M, Schroeder CM, Trautwein N, Hilke FJ, Zinser RS, Mühlenbruch L, Kowalewski DJ, Schuster H, Sturm M, Matthes J, Riess O, Czemmel S, Nahnsen S, Königsrainer I, Thiel K, Nadalin S, Beckert S, Bösmüller H, Fend F, Velic A, Maček B, Haen SP, Buonaguro L, Kohlbacher O, Stevanović S, Königsrainer A; HEPAVAC Consortium; Rammensee HG. Löffler MW, et al. Among authors: nahnsen s. Genome Med. 2019 Apr 30;11(1):28. doi: 10.1186/s13073-019-0636-8. Genome Med. 2019. PMID: 31039795 Free PMC article.
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