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Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects.
Gopalswamy M, Kroeger T, Bickel D, Frieg B, Akter S, Schott-Verdugo S, Viegas A, Pauly T, Mayer M, Przibilla J, Reiners J, Nagel-Steger L, Smits SHJ, Groth G, Etzkorn M, Gohlke H. Gopalswamy M, et al. Among authors: nagel steger l. Sci Rep. 2022 Aug 19;12(1):14158. doi: 10.1038/s41598-022-17913-6. Sci Rep. 2022. PMID: 35986043 Free PMC article.
Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response.
Bhatia S, Diedrich D, Frieg B, Ahlert H, Stein S, Bopp B, Lang F, Zang T, Kröger T, Ernst T, Kögler G, Krieg A, Lüdeke S, Kunkel H, Rodrigues Moita AJ, Kassack MU, Marquardt V, Opitz FV, Oldenburg M, Remke M, Babor F, Grez M, Hochhaus A, Borkhardt A, Groth G, Nagel-Steger L, Jose J, Kurz T, Gohlke H, Hansen FK, Hauer J. Bhatia S, et al. Blood. 2018 Jul 19;132(3):307-320. doi: 10.1182/blood-2017-10-810986. Epub 2018 May 3. Blood. 2018. PMID: 29724897 Free PMC article.
Posttranslational Modification of the NADP-Malic Enzyme Involved in C4 Photosynthesis Modulates the Enzymatic Activity during the Day.
Bovdilova A, Alexandre BM, Höppner A, Luís IM, Alvarez CE, Bickel D, Gohlke H, Decker C, Nagel-Steger L, Alseekh S, Fernie AR, Drincovich MF, Abreu IA, Maurino VG. Bovdilova A, et al. Among authors: nagel steger l. Plant Cell. 2019 Oct;31(10):2525-2539. doi: 10.1105/tpc.19.00406. Epub 2019 Jul 30. Plant Cell. 2019. PMID: 31363039 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33590091
60 results