Nagata Y - Search Results

1

The intestinal first-pass metabolism of substrates of CYP3A4 and P-glycoprotein-quantitative analysis based on information from the literature.

Kato M, Chiba K, Hisaka A, Ishigami M, Kayama M, Mizuno N, Nagata Y, Takakuwa S, Tsukamoto Y, Ueda K, Kusuhara H, Ito K, Sugiyama Y. Kato M, et al. Among authors: nagata y. Drug Metab Pharmacokinet. 2003;18(6):365-72. doi: 10.2133/dmpk.18.365. Drug Metab Pharmacokinet. 2003. PMID: 15618757 Free article.

2

Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3.

Nagata Y, Kusuhara H, Hirono S, Endou H, Sugiyama Y. Nagata Y, et al. Drug Metab Dispos. 2004 Sep;32(9):1040-7. Drug Metab Dispos. 2004. PMID: 15319347

3

Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus.

Nagata Y, Kusuhara H, Endou H, Sugiyama Y. Nagata Y, et al. Mol Pharmacol. 2002 May;61(5):982-8. doi: 10.1124/mol.61.5.982. Mol Pharmacol. 2002. PMID: 11961115

4

Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroid plexus.

Nagata Y, Kusuhara H, Imaoka T, Endou H, Sugiyama Y. Nagata Y, et al. J Pharm Sci. 2004 Nov;93(11):2724-32. doi: 10.1002/jps.20175. J Pharm Sci. 2004. PMID: 15389674

5

Expression and functional involvement of organic anion transporting polypeptide subtype 3 (Slc21a7) in rat choroid plexus.

Kusuhara H, He Z, Nagata Y, Nozaki Y, Ito T, Masuda H, Meier PJ, Abe T, Sugiyama Y. Kusuhara H, et al. Among authors: nagata y. Pharm Res. 2003 May;20(5):720-7. doi: 10.1023/a:1023473216759. Pharm Res. 2003. PMID: 12751626

6

N-[2-[N'-pentyl-(6,6-dimethyl-2,4-heptadiynyl)amino]ethyl]- (2-methyl-1-naphthylthio)acetamide (FY-087). A new acyl coenzyme a:cholesterol acyltransferase (ACAT) inhibitor of diet-induced atherosclerosis formation in mice.

Nagata Y, Yonemoto M, Iwasawa Y, Shimizu-Nagumo A, Hattori H, Sawazaki Y, Kamei T. Nagata Y, et al. Biochem Pharmacol. 1995 Mar 1;49(5):643-51. doi: 10.1016/0006-2952(94)00510-s. Biochem Pharmacol. 1995. PMID: 7887979

7

Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells.

Hidaka Y, Hotta H, Nagata Y, Iwasawa Y, Horie M, Kamei T. Hidaka Y, et al. Among authors: nagata y. J Biol Chem. 1991 Jul 15;266(20):13171-7. J Biol Chem. 1991. PMID: 1649182 Free article.

Furthermore, multiple oral administration of NB-598 decreased serum cholesterol levels in dogs (Horie, M., Tsuchiya, Y., Hayashi, M., Iida, Y., Iwasawa, Y., Nagata, Y., Sawasaki, Y., Fukuzumi, H., Kitani, K., and Kamei, T. (1990) J. ...

Furthermore, multiple oral administration of NB-598 decreased serum cholesterol levels in dogs (Horie, M., Tsuchiya, Y., Hayashi, M., …

8

An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells.

Horie M, Hayashi M, Satoh T, Hotta H, Nagata Y, Ishida F, Kamei T. Horie M, et al. Among authors: nagata y. Biochim Biophys Acta. 1993 May 20;1168(1):45-51. Biochim Biophys Acta. 1993. PMID: 8504141

9

NB-598: a potent competitive inhibitor of squalene epoxidase.

Horie M, Tsuchiya Y, Hayashi M, Iida Y, Iwasawa Y, Nagata Y, Sawasaki Y, Fukuzumi H, Kitani K, Kamei T. Horie M, et al. Among authors: nagata y. J Biol Chem. 1990 Oct 25;265(30):18075-8. J Biol Chem. 1990. PMID: 2211682 Free article.

10

Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells.

Horie M, Iwasawa Y, Satoh T, Shimizu A, Nagata Y, Kamei T. Horie M, et al. Among authors: nagata y. Biochem Pharmacol. 1993 Jul 20;46(2):297-305. doi: 10.1016/0006-2952(93)90418-v. Biochem Pharmacol. 1993. PMID: 8347152

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