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ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury.
Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka MN, Niiyama M, Imai M, Uda A, Chan JF, Takahashi S, An J, Saku A, Nukiwa R, Utsumi D, Kiso M, Yasuhara A, Poon VK, Chan CC, Fujino Y, Motoyama S, Nagata S, Penninger JM, Kamada H, Yuen KY, Kamitani W, Maeda K, Kawaoka Y, Yasutomi Y, Imai Y, Kuba K. Yamaguchi T, et al. Among authors: nagata s. Nat Commun. 2021 Nov 23;12(1):6791. doi: 10.1038/s41467-021-27097-8. Nat Commun. 2021. PMID: 34815389 Free PMC article.
COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions.
Urano E, Okamura T, Ono C, Ueno S, Nagata S, Kamada H, Higuchi M, Furukawa M, Kamitani W, Matsuura Y, Kawaoka Y, Yasutomi Y. Urano E, et al. Among authors: nagata s. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2104847118. doi: 10.1073/pnas.2104847118. Proc Natl Acad Sci U S A. 2021. PMID: 34625475 Free PMC article.
Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window.
Shibata H, Yoshioka Y, Ikemizu S, Kobayashi K, Yamamoto Y, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Hayakawa T, Nagata S, Yamagata Y, Mayumi T, Kamada H, Tsutsumi Y. Shibata H, et al. Among authors: nagata s. Clin Cancer Res. 2004 Dec 15;10(24):8293-300. doi: 10.1158/1078-0432.CCR-04-0770. Clin Cancer Res. 2004. PMID: 15623605
Optimal site-specific PEGylation of mutant TNF-alpha improves its antitumor potency.
Yoshioka Y, Tsutsumi Y, Ikemizu S, Yamamoto Y, Shibata H, Nishibata T, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Nagata S, Yamagata Y, Mayumi T. Yoshioka Y, et al. Among authors: nagata s. Biochem Biophys Res Commun. 2004 Mar 19;315(4):808-14. doi: 10.1016/j.bbrc.2004.01.125. Biochem Biophys Res Commun. 2004. PMID: 14985084
Site-specific PEGylation of a lysine-deficient TNF-alpha with full bioactivity.
Yamamoto Y, Tsutsumi Y, Yoshioka Y, Nishibata T, Kobayashi K, Okamoto T, Mukai Y, Shimizu T, Nakagawa S, Nagata S, Mayumi T. Yamamoto Y, et al. Among authors: nagata s. Nat Biotechnol. 2003 May;21(5):546-52. doi: 10.1038/nbt812. Epub 2003 Mar 31. Nat Biotechnol. 2003. PMID: 12665803
2,108 results