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Page 1
Structural enzymology using X-ray free electron lasers.
Kupitz C, Olmos JL Jr, Holl M, Tremblay L, Pande K, Pandey S, Oberthür D, Hunter M, Liang M, Aquila A, Tenboer J, Calvey G, Katz A, Chen Y, Wiedorn MO, Knoska J, Meents A, Majriani V, Norwood T, Poudyal I, Grant T, Miller MD, Xu W, Tolstikova A, Morgan A, Metz M, Martin-Garcia JM, Zook JD, Roy-Chowdhury S, Coe J, Nagaratnam N, Meza D, Fromme R, Basu S, Frank M, White T, Barty A, Bajt S, Yefanov O, Chapman HN, Zatsepin N, Nelson G, Weierstall U, Spence J, Schwander P, Pollack L, Fromme P, Ourmazd A, Phillips GN Jr, Schmidt M. Kupitz C, et al. Among authors: nagaratnam n. Struct Dyn. 2016 Dec 15;4(4):044003. doi: 10.1063/1.4972069. eCollection 2017 Jul. Struct Dyn. 2016. PMID: 28083542 Free PMC article.
Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation.
Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J, Zhu L, Geiger J, Chun E, Kissick D, Hilgart MC, Ogata C, Ishchenko A, Nagaratnam N, Roy-Chowdhury S, Coe J, Subramanian G, Schaffer A, James D, Ketwala G, Venugopalan N, Xu S, Corcoran S, Ferguson D, Weierstall U, Spence JCH, Cherezov V, Fromme P, Fischetti RF, Liu W. Martin-Garcia JM, et al. Among authors: nagaratnam n. IUCrJ. 2017 May 24;4(Pt 4):439-454. doi: 10.1107/S205225251700570X. eCollection 2017 Jul 1. IUCrJ. 2017. PMID: 28875031 Free PMC article.
Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
Olmos JL Jr, Pandey S, Martin-Garcia JM, Calvey G, Katz A, Knoska J, Kupitz C, Hunter MS, Liang M, Oberthuer D, Yefanov O, Wiedorn M, Heyman M, Holl M, Pande K, Barty A, Miller MD, Stern S, Roy-Chowdhury S, Coe J, Nagaratnam N, Zook J, Verburgt J, Norwood T, Poudyal I, Xu D, Koglin J, Seaberg MH, Zhao Y, Bajt S, Grant T, Mariani V, Nelson G, Subramanian G, Bae E, Fromme R, Fung R, Schwander P, Frank M, White TA, Weierstall U, Zatsepin N, Spence J, Fromme P, Chapman HN, Pollack L, Tremblay L, Ourmazd A, Phillips GN Jr, Schmidt M. Olmos JL Jr, et al. Among authors: nagaratnam n. BMC Biol. 2018 May 31;16(1):59. doi: 10.1186/s12915-018-0524-5. BMC Biol. 2018. PMID: 29848358 Free PMC article.
Enhanced X-ray diffraction of in vivo-grown μNS crystals by viscous jets at XFELs.
Nagaratnam N, Tang Y, Botha S, Saul J, Li C, Hu H, Zaare S, Hunter M, Lowry D, Weierstall U, Zatsepin N, Spence JCH, Qiu J, LaBaer J, Fromme P, Martin-Garcia JM. Nagaratnam N, et al. Acta Crystallogr F Struct Biol Commun. 2020 Jun 1;76(Pt 6):278-289. doi: 10.1107/S2053230X20006172. Epub 2020 May 29. Acta Crystallogr F Struct Biol Commun. 2020. PMID: 32510469 Free PMC article.
Structural insights into the function of the catalytically active human Taspase1.
Nagaratnam N, Delker SL, Jernigan R, Edwards TE, Snider J, Thifault D, Williams D, Nannenga BL, Stofega M, Sambucetti L, Hsieh JJ, Flint AJ, Fromme P, Martin-Garcia JM. Nagaratnam N, et al. Structure. 2021 Aug 5;29(8):873-885.e5. doi: 10.1016/j.str.2021.03.008. Epub 2021 Mar 29. Structure. 2021. PMID: 33784495 Free article.
Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser.
Jernigan RJ, Logeswaran D, Doppler D, Nagaratnam N, Sonker M, Yang JH, Ketawala G, Martin-Garcia JM, Shelby ML, Grant TD, Mariani V, Tolstikova A, Sheikh MZ, Yung MC, Coleman MA, Zaare S, Kaschner EK, Rabbani MT, Nazari R, Zacks MA, Hayes B, Sierra RG, Hunter MS, Lisova S, Batyuk A, Kupitz C, Boutet S, Hansen DT, Kirian RA, Schmidt M, Fromme R, Frank M, Ros A, Chen JJ, Botha S, Fromme P. Jernigan RJ, et al. Among authors: nagaratnam n. Structure. 2023 Feb 2;31(2):138-151.e5. doi: 10.1016/j.str.2022.12.009. Epub 2023 Jan 10. Structure. 2023. PMID: 36630960 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36783981
Impaired mitophagosome-lysosome fusion mediates olanzapine-induced aging.
Chen X, Wang Z, Zheng P, Dongol A, Xie Y, Ge X, Zheng M, Dang X, Seyhan ZB, Nagaratnam N, Yu Y, Huang XF. Chen X, et al. Among authors: nagaratnam n. Aging Cell. 2023 Nov;22(11):e14003. doi: 10.1111/acel.14003. Epub 2023 Oct 13. Aging Cell. 2023. PMID: 37828862 Free PMC article.
133 results