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Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist.
Kawai T, Sun B, Yoshino H, Feng D, Suzuki Y, Fukazawa M, Nagao S, Wainscott DB, Showalter AD, Droz BA, Kobilka TS, Coghlan MP, Willard FS, Kawabe Y, Kobilka BK, Sloop KW. Kawai T, et al. Among authors: nagao s. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29959-29967. doi: 10.1073/pnas.2014879117. Epub 2020 Nov 11. Proc Natl Acad Sci U S A. 2020. PMID: 33177239 Free PMC article.
In vitro profiling of the metabolism and drug-drug interaction of tofogliflozin, a potent and highly specific sodium-glucose co-transporter 2 inhibitor, using human liver microsomes, human hepatocytes, and recombinant human CYP.
Yamane M, Kawashima K, Yamaguchi K, Nagao S, Sato M, Suzuki M, Honda K, Hagita H, Kuhlmann O, Poirier A, Fowler S, Funk C, Simon S, Aso Y, Ikeda S, Ishigai M. Yamane M, et al. Among authors: nagao s. Xenobiotica. 2015 Mar;45(3):230-8. doi: 10.3109/00498254.2014.976296. Epub 2014 Oct 28. Xenobiotica. 2015. PMID: 25350082
A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts.
Endo M, Miwa M, Ura M, Tanimura H, Taniguchi K, Miyazaki Y, Ohwada J, Tsukazaki M, Niizuma S, Murata T, Ozawa S, Suda H, Ogawa K, Nanba E, Nagao S, Shimma N, Yamada-Okabe H. Endo M, et al. Among authors: nagao s. Cancer Chemother Pharmacol. 2010 Jan;65(2):363-71. doi: 10.1007/s00280-009-1042-5. Cancer Chemother Pharmacol. 2010. PMID: 19495753
Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog.
Ohwada J, Ozawa S, Kohchi M, Fukuda H, Murasaki C, Suda H, Murata T, Niizuma S, Tsukazaki M, Ori K, Yoshinari K, Itezono Y, Endo M, Ura M, Tanimura H, Miyazaki Y, Kawashima A, Nagao S, Namba E, Ogawa K, Kobayashi K, Okabe H, Umeda I, Shimma N. Ohwada J, et al. Among authors: nagao s. Bioorg Med Chem Lett. 2009 May 15;19(10):2772-6. doi: 10.1016/j.bmcl.2009.03.123. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19362835
Novel Measurement of the Neutron Magnetic Form Factor from A=3 Mirror Nuclei.
Santiesteban SN, Li S, Abrams D, Alsalmi S, Androic D, Aniol K, Arrington J, Averett T, Ayerbe Gayoso C, Bane J, Barcus S, Barrow J, Beck A, Bellini V, Bhatt H, Bhetuwal D, Biswas D, Camsonne A, Castellanos J, Chen J, Chen JP, Chrisman D, Christy ME, Clarke C, Covrig S, Cruz-Torres R, Day D, Dutta D, Fuchey E, Gal C, Garibaldi F, Gautam TN, Gogami T, Gomez J, Guèye P, Hague TJ, Hansen JO, Hauenstein F, Henry W, Higinbotham DW, Holt RJ, Hyde C, Itabashi K, Kaneta M, Karki A, Katramatou AT, Keppel CE, King PM, Kurbany L, Kutz T, Lashley-Colthirst N, Li WB, Liu H, Liyanage N, Long E, Lovato A, Mammei J, Markowitz P, McClellan RE, Meddi F, Meekins D, Michaels R, Mihovilovič M, Moyer A, Nagao S, Nguyen D, Nycz M, Olson M, Ou L, Owen V, Palatchi C, Pandey B, Papadopoulou A, Park S, Petkovic T, Premathilake S, Punjabi V, Ransome RD, Reimer PE, Reinhold J, Riordan S, Rocco N, Rodriguez VM, Schmidt A, Schmookler B, Segarra EP, Shahinyan A, Širca S, Slifer K, Solvignon P, Su T, Suleiman R, Tang L, Tian Y, Tireman W, Tortorici F, Toyama Y, Uehara K, Urciuoli GM, Votaw D, Williamson J, Wojtsekhowski B, Wood S, Ye ZH, Zhang J, Zheng X; Jefferson Lab Hall A Collaboration. Santiesteban SN, et al. Among authors: nagao s. Phys Rev Lett. 2024 Apr 19;132(16):162501. doi: 10.1103/PhysRevLett.132.162501. Phys Rev Lett. 2024. PMID: 38701469
1,115 results