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Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment.
Takeuchi M, Kimura S, Kuroda J, Ashihara E, Kawatani M, Osada H, Umezawa K, Yasui E, Imoto M, Tsuruo T, Yokota A, Tanaka R, Nagao R, Nakahata T, Fujiyama Y, Maekawa T. Takeuchi M, et al. Among authors: nagao r. Cell Death Differ. 2010 Jul;17(7):1211-20. doi: 10.1038/cdd.2010.6. Epub 2010 Feb 5. Cell Death Differ. 2010. PMID: 20139893
Osteoclasts are involved in the maintenance of dormant leukemic cells.
Yokota A, Kimura S, Tanaka R, Takeuchi M, Yao H, Sakai K, Nagao R, Kuroda J, Kamitsuji Y, Kawata E, Ashihara E, Maekawa T. Yokota A, et al. Among authors: nagao r. Leuk Res. 2010 Jun;34(6):793-9. doi: 10.1016/j.leukres.2009.08.034. Epub 2009 Sep 24. Leuk Res. 2010. PMID: 19781772
Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients.
Tanaka R, Kimura S, Ashihara E, Yoshimura M, Takahashi N, Wakita H, Itoh K, Nishiwaki K, Suzuki K, Nagao R, Yao H, Hayashi Y, Satake S, Hirai H, Sawada K, Ottmann OG, Melo JV, Maekawa T. Tanaka R, et al. Among authors: nagao r. Cancer Lett. 2011 Dec 22;312(2):228-34. doi: 10.1016/j.canlet.2011.08.009. Epub 2011 Aug 22. Cancer Lett. 2011. PMID: 21890264
Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis.
Sakai K, Kawata E, Ashihara E, Nakagawa Y, Yamauchi A, Yao H, Nagao R, Tanaka R, Yokota A, Takeuchi M, Hirai H, Kimura S, Hirashima M, Yoshimura N, Maekawa T. Sakai K, et al. Among authors: nagao r. Eur J Immunol. 2011 Jan;41(1):67-75. doi: 10.1002/eji.200939931. Epub 2010 Dec 9. Eur J Immunol. 2011. PMID: 21182078 Free article.
AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model.
Yao H, Ashihara E, Strovel JW, Nakagawa Y, Kuroda J, Nagao R, Tanaka R, Yokota A, Takeuchi M, Hayashi Y, Shimazaki C, Taniwaki M, Strand K, Padia J, Hirai H, Kimura S, Maekawa T. Yao H, et al. Among authors: nagao r. Blood Cancer J. 2011 Nov;1(11):e43. doi: 10.1038/bcj.2011.41. Epub 2011 Nov 4. Blood Cancer J. 2011. PMID: 22829079 Free PMC article.
249 results