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FGFR2 maintains cancer cell differentiation via AKT signaling in esophageal squamous cell carcinoma.
Maehara O, Suda G, Natsuizaka M, Shigesawa T, Kanbe G, Kimura M, Sugiyama M, Mizokami M, Nakai M, Sho T, Morikawa K, Ogawa K, Ohashi S, Kagawa S, Kinugasa H, Naganuma S, Okubo N, Ohnishi S, Takeda H, Sakamoto N. Maehara O, et al. Among authors: naganuma s. Cancer Biol Ther. 2021 Jun 3;22(5-6):372-380. doi: 10.1080/15384047.2021.1939638. Epub 2021 Jul 5. Cancer Biol Ther. 2021. PMID: 34224333 Free PMC article.
Fibroblast growth factor-2-mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma.
Maehara O, Suda G, Natsuizaka M, Ohnishi S, Komatsu Y, Sato F, Nakai M, Sho T, Morikawa K, Ogawa K, Shimazaki T, Kimura M, Asano A, Fujimoto Y, Ohashi S, Kagawa S, Kinugasa H, Naganuma S, Whelan KA, Nakagawa H, Nakagawa K, Takeda H, Sakamoto N. Maehara O, et al. Among authors: naganuma s. Carcinogenesis. 2017 Oct 26;38(11):1073-1083. doi: 10.1093/carcin/bgx095. Carcinogenesis. 2017. PMID: 28927233 Free PMC article.
A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.
Ohashi S, Natsuizaka M, Naganuma S, Kagawa S, Kimura S, Itoh H, Kalman RA, Nakagawa M, Darling DS, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Herlyn M, Nakagawa H. Ohashi S, et al. Among authors: naganuma s. Cancer Res. 2011 Nov 1;71(21):6836-47. doi: 10.1158/0008-5472.CAN-11-0846. Epub 2011 Sep 2. Cancer Res. 2011. PMID: 21890822 Free PMC article.
Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.
Natsuizaka M, Whelan KA, Kagawa S, Tanaka K, Giroux V, Chandramouleeswaran PM, Long A, Sahu V, Darling DS, Que J, Yang Y, Katz JP, Wileyto EP, Basu D, Kita Y, Natsugoe S, Naganuma S, Klein-Szanto AJ, Diehl JA, Bass AJ, Wong KK, Rustgi AK, Nakagawa H. Natsuizaka M, et al. Among authors: naganuma s. Nat Commun. 2017 Nov 24;8(1):1758. doi: 10.1038/s41467-017-01500-9. Nat Commun. 2017. PMID: 29170450 Free PMC article.
Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.
Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H. Kagawa S, et al. Among authors: naganuma s. Oncogene. 2015 Apr 30;34(18):2347-59. doi: 10.1038/onc.2014.169. Epub 2014 Jun 16. Oncogene. 2015. PMID: 24931169 Free PMC article.
Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells.
Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran PM, Hara T, Sahu V, Kasagi Y, Kikuchi O, Tanaka K, Giroux V, Muir AB, Whelan KA, Ohashi S, Naganuma S, Klein-Szanto AJ, Shinden Y, Sasaki K, Omoto I, Kita Y, Muto M, Bass AJ, Diehl JA, Ginsberg GG, Doki Y, Mori M, Uchikado Y, Arigami T, Avadhani NG, Basu D, Rustgi AK, Natsugoe S. Kijima T, et al. Among authors: naganuma s. Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):73-91. doi: 10.1016/j.jcmgh.2018.09.003. eCollection 2019. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30510992 Free PMC article.
121 results