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Taspine is a natural product that suppresses P2X4 receptor activity via phosphoinositide 3-kinase inhibition.
Br J Pharmacol. 2021 Dec;178(24):4859-4872. doi: 10.1111/bph.15663. Epub 2021 Sep 21.
Br J Pharmacol. 2021.
PMID: 34398973
Free article.
Structural Basis of the Negative Allosteric Modulation of 5-BDBD at Human P2X4 Receptors.
Bidula S, Nadzirin IB, Cominetti M, Hickey H, Cullum SA, Searcey M, Schmid R, Fountain SJ.
Bidula S, et al. Among authors: nadzirin ib.
Mol Pharmacol. 2022 Jan;101(1):33-44. doi: 10.1124/molpharm.121.000402. Epub 2021 Oct 30.
Mol Pharmacol. 2022.
PMID: 34718224
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