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Nuclear fragility, blaming the blebs.
Srivastava N, Nader GPF, Williart A, Rollin R, Cuvelier D, Lomakin A, Piel M. Srivastava N, et al. Among authors: nader gpf. Curr Opin Cell Biol. 2021 Jun;70:100-108. doi: 10.1016/j.ceb.2021.01.007. Epub 2021 Mar 1. Curr Opin Cell Biol. 2021. PMID: 33662810 Review.
Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion.
Nader GPF, Agüera-Gonzalez S, Routet F, Gratia M, Maurin M, Cancila V, Cadart C, Palamidessi A, Ramos RN, San Roman M, Gentili M, Yamada A, Williart A, Lodillinsky C, Lagoutte E, Villard C, Viovy JL, Tripodo C, Galon J, Scita G, Manel N, Chavrier P, Piel M. Nader GPF, et al. Cell. 2021 Sep 30;184(20):5230-5246.e22. doi: 10.1016/j.cell.2021.08.035. Epub 2021 Sep 21. Cell. 2021. PMID: 34551315 Free article.
Nuclear envelope disruption triggers hallmarks of aging in lung alveolar macrophages.
De Silva NS, Siewiera J, Alkhoury C, Nader GPF, Nadalin F, de Azevedo K, Couty M, Izquierdo HM, Bhargava A, Conrad C, Maurin M, Antoniadou K, Fouillade C, Londono-Vallejo A, Behrendt R, Bertotti K, Serdjebi C, Lanthiez F, Gallwitz L, Saftig P, Herrero-Fernández B, Saez A, González-Granado JM, van Niel G, Boissonnas A, Piel M, Manel N. De Silva NS, et al. Among authors: nader gpf. Nat Aging. 2023 Oct;3(10):1251-1268. doi: 10.1038/s43587-023-00488-w. Epub 2023 Sep 18. Nat Aging. 2023. PMID: 37723209
The nucleus acts as a ruler tailoring cell responses to spatial constraints.
Lomakin AJ, Cattin CJ, Cuvelier D, Alraies Z, Molina M, Nader GPF, Srivastava N, Sáez PJ, Garcia-Arcos JM, Zhitnyak IY, Bhargava A, Driscoll MK, Welf ES, Fiolka R, Petrie RJ, De Silva NS, González-Granado JM, Manel N, Lennon-Duménil AM, Müller DJ, Piel M. Lomakin AJ, et al. Among authors: nader gpf. Science. 2020 Oct 16;370(6514):eaba2894. doi: 10.1126/science.aba2894. Science. 2020. PMID: 33060332 Free PMC article.
The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.
Gentili M, Lahaye X, Nadalin F, Nader GPF, Lombardi EP, Herve S, De Silva NS, Rookhuizen DC, Zueva E, Goudot C, Maurin M, Bochnakian A, Amigorena S, Piel M, Fachinetti D, Londoño-Vallejo A, Manel N. Gentili M, et al. Among authors: nader gpf. Cell Rep. 2019 Mar 26;26(13):3798. doi: 10.1016/j.celrep.2019.03.049. Cell Rep. 2019. PMID: 30917330 Free PMC article. No abstract available.
The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.
Gentili M, Lahaye X, Nadalin F, Nader GPF, Puig Lombardi E, Herve S, De Silva NS, Rookhuizen DC, Zueva E, Goudot C, Maurin M, Bochnakian A, Amigorena S, Piel M, Fachinetti D, Londoño-Vallejo A, Manel N. Gentili M, et al. Among authors: nader gpf. Cell Rep. 2019 Feb 26;26(9):2377-2393.e13. doi: 10.1016/j.celrep.2019.01.105. Cell Rep. 2019. PMID: 30811988 Free PMC article.
11 results