Nacro K - Search Results

1

Topography of transcriptionally active chromatin in glioblastoma.

Xu L, Chen Y, Huang Y, Sandanaraj E, Yu JS, Lin RY, Dakle P, Ke XY, Chong YK, Koh L, Mayakonda A, Nacro K, Hill J, Huang ML, Gery S, Lim SW, Huang Z, Xu Y, Chen J, Bai L, Wang S, Wakimoto H, Yeo TT, Ang BT, Müschen M, Tang C, Tan TZ, Koeffler HP. Xu L, et al. Among authors: nacro k. Sci Adv. 2021 Apr 30;7(18):eabd4676. doi: 10.1126/sciadv.abd4676. Print 2021 Apr. Sci Adv. 2021. PMID: 33931443 Free PMC article.

2

MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma.

Ke XY, Chen Y, Tham VY, Lin RY, Dakle P, Nacro K, Puhaindran ME, Houghton P, Pang A, Lee VK, Ding LW, Gery S, Hill J, Chen L, Xu L, Koeffler HP. Ke XY, et al. Among authors: nacro k. Oncogene. 2021 Mar;40(10):1851-1867. doi: 10.1038/s41388-021-01661-4. Epub 2021 Feb 9. Oncogene. 2021. PMID: 33564073 Free PMC article.

3

Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function.

Lim S, Saw TY, Zhang M, Janes MR, Nacro K, Hill J, Lim AQ, Chang CT, Fruman DA, Rizzieri DA, Tan SY, Fan H, Chuah CT, Ong ST. Lim S, et al. Among authors: nacro k. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2298-307. doi: 10.1073/pnas.1301838110. Epub 2013 Jun 4. Proc Natl Acad Sci U S A. 2013. PMID: 23737503 Free PMC article.

4

Identification of covalent active site inhibitors of dengue virus protease.

Koh-Stenta X, Joy J, Wang SF, Kwek PZ, Wee JL, Wan KF, Gayen S, Chen AS, Kang C, Lee MA, Poulsen A, Vasudevan SG, Hill J, Nacro K. Koh-Stenta X, et al. Among authors: nacro k. Drug Des Devel Ther. 2015 Dec 10;9:6389-99. doi: 10.2147/DDDT.S94207. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26677315 Free PMC article.

5

Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor.

Li Y, Zhang Z, Phoo WW, Loh YR, Li R, Yang HY, Jansson AE, Hill J, Keller TH, Nacro K, Luo D, Kang C. Li Y, et al. Among authors: nacro k. Structure. 2018 Apr 3;26(4):555-564.e3. doi: 10.1016/j.str.2018.02.005. Epub 2018 Mar 8. Structure. 2018. PMID: 29526431 Free article.

6

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening.

Enyedy IJ, Ling Y, Nacro K, Tomita Y, Wu X, Cao Y, Guo R, Li B, Zhu X, Huang Y, Long YQ, Roller PP, Yang D, Wang S. Enyedy IJ, et al. Among authors: nacro k. J Med Chem. 2001 Dec 6;44(25):4313-24. doi: 10.1021/jm010016f. J Med Chem. 2001. PMID: 11728179

7

Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions.

Wang QJ, Fang TW, Nacro K, Marquez VE, Wang S, Blumberg PM. Wang QJ, et al. Among authors: nacro k. J Biol Chem. 2001 Jun 1;276(22):19580-7. doi: 10.1074/jbc.M010089200. Epub 2001 Mar 14. J Biol Chem. 2001. PMID: 11278612 Free article.

8

Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2.

Kwiatkowski J, Liu B, Pang S, Ahmad NHB, Wang G, Poulsen A, Yang H, Poh YR, Tee DHY, Ong E, Retna P, Dinie N, Kwek P, Wee JLK, Manoharan V, Low CB, Seah PG, Pendharkar V, Sangthongpitag K, Joy J, Baburajendran N, Jansson AE, Nacro K, Hill J, Keller TH, Hung AW. Kwiatkowski J, et al. Among authors: nacro k. J Med Chem. 2020 Jan 23;63(2):621-637. doi: 10.1021/acs.jmedchem.9b01582. Epub 2020 Jan 7. J Med Chem. 2020. PMID: 31910010

9

The transition from a pharmacophore-guided approach to a receptor-guided approach in the design of potent protein kinase C ligands.

Marquez VE, Nacro K, Benzaria S, Lee J, Sharma R, Teng K, Milne GW, Bienfait B, Wang S, Lewin NE, Blumberg PM. Marquez VE, et al. Among authors: nacro k. Pharmacol Ther. 1999 May-Jun;82(2-3):251-61. doi: 10.1016/s0163-7258(98)00048-5. Pharmacol Ther. 1999. PMID: 10454202 Review.

10

Conformationally constrained analogues of diacylglycerol (DAG). 15. The indispensable role of the sn-1 and sn-2 carbonyls in the binding of DAG-lactones to protein kinase C (PK-C).

Benzaria S, Bienfait B, Nacro K, Wang S, Lewin NE, Beheshti M, Blumberg PM, Marquez VE. Benzaria S, et al. Among authors: nacro k. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3403-8. doi: 10.1016/s0960-894x(98)00614-3. Bioorg Med Chem Lett. 1998. PMID: 9873742

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