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SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs.
Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Bauer MR, Taylor HB, Conway HL, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Keskin DB, Rice CM, Clauser KR, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC. Weingarten-Gabbay S, et al. Among authors: nachshon a. bioRxiv [Preprint]. 2020 Oct 26:2020.10.02.324145. doi: 10.1101/2020.10.02.324145. bioRxiv. 2020. PMID: 33024965 Free PMC article. Preprint.
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs.
Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, Leistritz-Edwards D, Durkin MR, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Carulli IP, Chea VA, Chandrashekar A, Bozkus CC, Carrington M; MGH COVID-19 Collection & Processing Team; Bhardwaj N, Barouch DH, Sette A, Maus MV, Rice CM, Clauser KR, Keskin DB, Pregibon DC, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC. Weingarten-Gabbay S, et al. Among authors: nachshon a. Cell. 2021 Jul 22;184(15):3962-3980.e17. doi: 10.1016/j.cell.2021.05.046. Epub 2021 Jun 3. Cell. 2021. PMID: 34171305 Free PMC article.
The coding capacity of SARS-CoV-2.
Finkel Y, Mizrahi O, Nachshon A, Weingarten-Gabbay S, Morgenstern D, Yahalom-Ronen Y, Tamir H, Achdout H, Stein D, Israeli O, Beth-Din A, Melamed S, Weiss S, Israely T, Paran N, Schwartz M, Stern-Ginossar N. Finkel Y, et al. Among authors: nachshon a. Nature. 2021 Jan;589(7840):125-130. doi: 10.1038/s41586-020-2739-1. Epub 2020 Sep 9. Nature. 2021. PMID: 32906143
SARS-CoV-2 uses a multipronged strategy to impede host protein synthesis.
Finkel Y, Gluck A, Nachshon A, Winkler R, Fisher T, Rozman B, Mizrahi O, Lubelsky Y, Zuckerman B, Slobodin B, Yahalom-Ronen Y, Tamir H, Ulitsky I, Israely T, Paran N, Schwartz M, Stern-Ginossar N. Finkel Y, et al. Among authors: nachshon a. Nature. 2021 Jun;594(7862):240-245. doi: 10.1038/s41586-021-03610-3. Epub 2021 May 12. Nature. 2021. PMID: 33979833
Parsing the role of NSP1 in SARS-CoV-2 infection.
Fisher T, Gluck A, Narayanan K, Kuroda M, Nachshon A, Hsu JC, Halfmann PJ, Yahalom-Ronen Y, Tamir H, Finkel Y, Schwartz M, Weiss S, Tseng CK, Israely T, Paran N, Kawaoka Y, Makino S, Stern-Ginossar N. Fisher T, et al. Among authors: nachshon a. Cell Rep. 2022 Jun 14;39(11):110954. doi: 10.1016/j.celrep.2022.110954. Epub 2022 May 26. Cell Rep. 2022. PMID: 35671758 Free PMC article.
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection.
Li B, Clohisey SM, Chia BS, Wang B, Cui A, Eisenhaure T, Schweitzer LD, Hoover P, Parkinson NJ, Nachshon A, Smith N, Regan T, Farr D, Gutmann MU, Bukhari SI, Law A, Sangesland M, Gat-Viks I, Digard P, Vasudevan S, Lingwood D, Dockrell DH, Doench JG, Baillie JK, Hacohen N. Li B, et al. Among authors: nachshon a. Nat Commun. 2020 Jan 9;11(1):164. doi: 10.1038/s41467-019-13965-x. Nat Commun. 2020. PMID: 31919360 Free PMC article.
Human cytomegalovirus long noncoding RNA4.9 regulates viral DNA replication.
Tai-Schmiedel J, Karniely S, Lau B, Ezra A, Eliyahu E, Nachshon A, Kerr K, Suárez N, Schwartz M, Davison AJ, Stern-Ginossar N. Tai-Schmiedel J, et al. Among authors: nachshon a. PLoS Pathog. 2020 Apr 15;16(4):e1008390. doi: 10.1371/journal.ppat.1008390. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32294138 Free PMC article.
43 results