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Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism.
Acta Neuropathol. 2023 May;145(5):573-595. doi: 10.1007/s00401-023-02555-3. Epub 2023 Mar 20.
Acta Neuropathol. 2023.
PMID: 36939875
Free PMC article.
Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson's disease.
Hideshima M, Kimura Y, Aguirre C, Kakuda K, Takeuchi T, Choong CJ, Doi J, Nabekura K, Yamaguchi K, Nakajima K, Baba K, Nagano S, Goto Y, Nagai Y, Mochizuki H, Ikenaka K.
Hideshima M, et al. Among authors: nabekura k.
Sci Rep. 2022 Jan 10;12(1):351. doi: 10.1038/s41598-021-04131-9.
Sci Rep. 2022.
PMID: 35013421
Free PMC article.
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