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Target Prediction of 5,10,15,20-Tetrakis(4'-Sulfonatophenyl)-Porphyrin Using Molecular Docking.
Udrea AM, Dinache A, Staicu A, Avram S. Udrea AM, et al. Pharmaceutics. 2022 Nov 5;14(11):2390. doi: 10.3390/pharmaceutics14112390. Pharmaceutics. 2022. PMID: 36365208 Free PMC article.
Our results indicate that this photosensitizer binds to several receptor targets, including B-cell lymphoma 2 (BCL-2) and other related proteins BCL-xL, MCL-1, or A1. ...We conclude that the studied porphyrin photosensitizer binds to human serum albumin and may inhibit the …
Our results indicate that this photosensitizer binds to several receptor targets, including B-cell lymphoma 2 (BCL-2) and other relat …
Low Blue Dose Photodynamic Therapy with Porphyrin-Iron Oxide Nanoparticles Complexes: In Vitro Study on Human Melanoma Cells.
Nistorescu S, Udrea AM, Badea MA, Lungu I, Boni M, Tozar T, Dumitrache F, Maraloiu VA, Popescu RG, Fleaca C, Andronescu E, Dinischiotu A, Staicu A, Balas M. Nistorescu S, et al. Pharmaceutics. 2021 Dec 10;13(12):2130. doi: 10.3390/pharmaceutics13122130. Pharmaceutics. 2021. PMID: 34959411 Free PMC article.
Biological tests revealed a high anticancer effect of gamma-Fe(2)O(3) NPs_TPPS complexes indi-cated by the inhibition of tumor cell proliferation, reduction of cell adhesion, and induction of cell death through ROS generated by TPPS under light exposure. ...
Biological tests revealed a high anticancer effect of gamma-Fe(2)O(3) NPs_TPPS complexes indi-cated by the inhibition of tumor cell p …