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Glutamine-derived aspartate is required for eIF5A hypusination-mediated translation of HIF-1α to induce the polarization of tumor-associated macrophages.
Exp Mol Med. 2024 May 1. doi: 10.1038/s12276-024-01214-1. Online ahead of print.
Exp Mol Med. 2024.
PMID: 38689086
Free article.
SGLT2 inhibitors prevent LPS-induced M1 macrophage polarization and alleviate inflammatory bowel disease by downregulating NHE1 expression.
Kim YJ, Jin J, Kim DH, Kim D, Lee YM, Byun JK, Choi YK, Park KG.
Kim YJ, et al.
Inflamm Res. 2023 Nov;72(10-11):1981-1997. doi: 10.1007/s00011-023-01796-y. Epub 2023 Sep 28.
Inflamm Res. 2023.
PMID: 37770568
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Macropinocytosis is an alternative pathway of cysteine acquisition and mitigates sorafenib-induced ferroptosis in hepatocellular carcinoma.
Byun JK, Lee S, Kang GW, Lee YR, Park SY, Song IS, Yun JW, Lee J, Choi YK, Park KG.
Byun JK, et al.
J Exp Clin Cancer Res. 2022 Mar 14;41(1):98. doi: 10.1186/s13046-022-02296-3.
J Exp Clin Cancer Res. 2022.
PMID: 35287706
Free PMC article.
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