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Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.
Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG. Godoy P, et al. Among authors: nussler a. Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23. Arch Toxicol. 2016. PMID: 27339419 Free PMC article.
Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells.
Ruhnke M, Ungefroren H, Nussler A, Martin F, Brulport M, Schormann W, Hengstler JG, Klapper W, Ulrichs K, Hutchinson JA, Soria B, Parwaresch RM, Heeckt P, Kremer B, Fändrich F. Ruhnke M, et al. Among authors: nussler a. Gastroenterology. 2005 Jun;128(7):1774-86. doi: 10.1053/j.gastro.2005.03.029. Gastroenterology. 2005. PMID: 15940611
Present status and perspectives of cell-based therapies for liver diseases.
Nussler A, Konig S, Ott M, Sokal E, Christ B, Thasler W, Brulport M, Gabelein G, Schormann W, Schulze M, Ellis E, Kraemer M, Nocken F, Fleig W, Manns M, Strom SC, Hengstler JG. Nussler A, et al. J Hepatol. 2006 Jul;45(1):144-59. doi: 10.1016/j.jhep.2006.04.002. Epub 2006 Apr 27. J Hepatol. 2006. PMID: 16730092 Review.
Generation of human hepatocytes by stem cell technology: definition of the hepatocyte.
Hengstler JG, Brulport M, Schormann W, Bauer A, Hermes M, Nussler AK, Fandrich F, Ruhnke M, Ungefroren H, Griffin L, Bockamp E, Oesch F, von Mach MA. Hengstler JG, et al. Among authors: nussler ak. Expert Opin Drug Metab Toxicol. 2005 Jun;1(1):61-74. doi: 10.1517/17425255.1.1.61. Expert Opin Drug Metab Toxicol. 2005. PMID: 16922653 Review.
Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.
Saussele T, Burk O, Blievernicht JK, Klein K, Nussler A, Nussler N, Hengstler JG, Eichelbaum M, Schwab M, Zanger UM. Saussele T, et al. Among authors: nussler n, nussler a. Clin Pharmacol Ther. 2007 Sep;82(3):265-74. doi: 10.1038/sj.clpt.6100138. Epub 2007 Mar 7. Clin Pharmacol Ther. 2007. PMID: 17344806
Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers.
Brulport M, Schormann W, Bauer A, Hermes M, Elsner C, Hammersen FJ, Beerheide W, Spitkovsky D, Härtig W, Nussler A, Horn LC, Edelmann J, Pelz-Ackermann O, Petersen J, Kamprad M, von Mach M, Lupp A, Zulewski H, Hengstler JG. Brulport M, et al. Among authors: nussler a. Hepatology. 2007 Sep;46(3):861-70. doi: 10.1002/hep.21745. Hepatology. 2007. PMID: 17668884
363 results