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Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin.
Hochheiser K, Wiede F, Wagner T, Freestone D, Enders MH, Olshansky M, Russ B, Nüssing S, Bawden E, Braun A, Bachem A, Gressier E, McConville R, Park SL, Jones CM, Davey GM, Gyorki DE, Tscharke D, Parish IA, Turner S, Herold MJ, Tiganis T, Bedoui S, Gebhardt T. Hochheiser K, et al. Among authors: nussing s. J Exp Med. 2021 Jun 7;218(6):e20200940. doi: 10.1084/jem.20200940. J Exp Med. 2021. PMID: 33914023 Free PMC article.
Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance.
Wagle MV, Vervoort SJ, Kelly MJ, Van Der Byl W, Peters TJ, Martin BP, Martelotto LG, Nüssing S, Ramsbottom KM, Torpy JR, Knight D, Reading S, Thia K, Miosge LA, Howard DR, Gloury R, Gabriel SS, Utzschneider DT, Oliaro J, Powell JD, Luciani F, Trapani JA, Johnstone RW, Kallies A, Goodnow CC, Parish IA. Wagle MV, et al. Among authors: nussing s. Nat Commun. 2021 May 13;12(1):2782. doi: 10.1038/s41467-021-23044-9. Nat Commun. 2021. PMID: 33986293 Free PMC article.
MYB orchestrates T cell exhaustion and response to checkpoint inhibition.
Tsui C, Kretschmer L, Rapelius S, Gabriel SS, Chisanga D, Knöpper K, Utzschneider DT, Nüssing S, Liao Y, Mason T, Torres SV, Wilcox SA, Kanev K, Jarosch S, Leube J, Nutt SL, Zehn D, Parish IA, Kastenmüller W, Shi W, Buchholz VR, Kallies A. Tsui C, et al. Among authors: nussing s. Nature. 2022 Sep;609(7926):354-360. doi: 10.1038/s41586-022-05105-1. Epub 2022 Aug 17. Nature. 2022. PMID: 35978192 Free PMC article.
Divergent SATB1 expression across human life span and tissue compartments.
Nüssing S, Koay HF, Sant S, Loudovaris T, Mannering SI, Lappas M, D Udekem Y, Konstantinov IE, Berzins SP, Rimmelzwaan GF, Turner SJ, Clemens EB, Godfrey DI, Nguyen TH, Kedzierska K. Nüssing S, et al. Immunol Cell Biol. 2019 May;97(5):498-511. doi: 10.1111/imcb.12233. Epub 2019 Feb 25. Immunol Cell Biol. 2019. PMID: 30803026 Free PMC article.
A divergent transcriptional landscape underpins the development and functional branching of MAIT cells.
Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, Sidwell T, Kallies A, Chen Z, Nüssing S, Kedzierska K, Mackay LK, McColl SR, Deenick EK, Fairlie DP, McCluskey J, Goodnow CC, Ritchie ME, Belz GT, Naik SH, Pellicci DG, Godfrey DI. Koay HF, et al. Among authors: nussing s. Sci Immunol. 2019 Nov 22;4(41):eaay6039. doi: 10.1126/sciimmunol.aay6039. Sci Immunol. 2019. PMID: 31757835 Free PMC article.
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